A comparative study of serum sodium and potassium levels between pre-eclamptic patients and normal pregnant women

Journal Title: Medpulse International Journal of Biochemistry - Year 2017, Vol 4, Issue 2

Abstract

Background: Hypertensive disorders in pregnancy are one of the major causes of maternal and perinatal mortality and morbidity. Though various factors like placental ischemia, immunological maladaptations, genetics and susceptible endothelium have been shown to play etiological role, the exact pathogenesis and complications of preeclampsia still remains undivulged. Of late, electrolyte imbalance is gaining prominence in the aetiopathogenesis of preeclampsia. Aim: To estimate and compare the serum levels of electrolytes like sodium and potassium between preeclamptic patients and normal pregnant women Materials and Methods: This was a case control study done in Pondicherry Institute of Medical Sciences with 50 preeclamptic patients as cases and 50 gestationally age matched normal pregnant women as controls. After getting informed consent, serum sodium and potassium levels were measured from both cases and controls. Results: Serum potassium levels were significantly decreased (p < 0.001) in cases when compared to controls. Further hyponatremia (p- 0.003) and hypokalemia (p- 0.001) were strongly associated with preeclampsia. Conclusion: Hyponatremia and hypokalemia were more prevelant in preeclamptic women. Proper monitoring and appropriate correction of these parameters during early pregnancy can prevent hypertensive complications in pregnancy.

Authors and Affiliations

V Naga Guhan, Sarita Basu, K Prabhakara Rao, Mary Daniel, S Arul Vijaya Vani

Keywords

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  • EP ID EP258972
  • DOI -
  • Views 135
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How To Cite

V Naga Guhan, Sarita Basu, K Prabhakara Rao, Mary Daniel, S Arul Vijaya Vani (2017). A comparative study of serum sodium and potassium levels between pre-eclamptic patients and normal pregnant women. Medpulse International Journal of Biochemistry, 4(2), 43-46. https://europub.co.uk/articles/-A-258972