A comparative study on two doses of clonidine 45mcg Vs 60mcg added to 0.5% hyperbaric upivacaine given intrathecally for infra umbilical surgeries
Journal Title: Medpulse International Journal of Anesthesiology - Year 2018, Vol 7, Issue 1
Abstract
Background: This study was designed to evaluate the addition of two doses of clonidine ( 45 μg and 60μg) added to hyperbaric bupivacaine (0.5%) 2.75ml in spinal anaesthesia for sub umbilical surgeries. Aim of Study: Time to onset of sensory and motor block, Duration of sensory and motor block, Duration of effective post operative analgesia, Side effects Materials and Methods: A total of 60 patients were included in this double blinded randomized controlled study. Patients were ivided into 3 groups. Patients in group B received 2.75ml of 0.5% hyperbaric bupivacaine plus 0.4ml saline. Patients in group C1 received 2.75ml of hyperbaric bupivacaine with 45μg of clonidine. Patients in group C2 received 2.75ml of hyperbaric bupivacaine with 60μg of clonidine. Results: The results showed that patients who received 2.75ml of hyperbaric bupivacaine with 60μg clonidine has proved to be a better adjuvant in prolonging the sensory and motor blockade intra operatively and duration of effective post operative analgesia compared to 45μg, without significant adverse effects.
Authors and Affiliations
Vivek T Menacherry, Aneesh Lakshmanan, Chittaranjan Sahu, P Narasimha Reddy
Keywords
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