Comparative study of hyperbaric bupivacaine and pentazocine in patients undergoing cesarean section under spinal anesthesia
Journal Title: Medpulse International Journal of Anesthesiology - Year 2019, Vol 9, Issue 2
Abstract
Background: The administration of opioids intrathecally as a sole anesthetic has proven to be effective in providing adequate surgical anesthesia without much hemodynamic instability. This study aims to determine the efficacy and safety of intrathecal Pentazocine as a sole anesthetic drug in patients undergoing lower segment caesarean section. Study Design: It was a randomized control double blinded study conducted in 200 patients undergoing lower segment caesarean section. Methods: The patients were randomly divided into 2 groups of 100 patients in each group. Group A received 1.5 ml (45 mg) intrathecal Pentazocine and Group B received 1.5ml intrathecal 0.5% Bupivacaine heavy before surgery. Duration of surgery, onset of sensory, and motor blockade and their duration, heart rate (HR), mean arterial pressure (MAP), and time for first rescue analgesia were statistically analyzed. Results: Onset of sensory blockade (2.65±0.78 vs 3.67±1.01 minutes) and motor blockade (2.43±1.13 vs 3.10±1.09 minutes) was earlier in Group A. Group B produced highest level of sensory blockade (T4) in majority of patients. Duration of analgesia is prolonged with Group B (2.46 ±0.496 vs 5.45±1.78 hours). Degree of motor blockade was better in group A, how ever duration of motor blockade was similar in both the groups. Group B patients were hemodynamically more stable intraoperatively and post operatively than Group A. Conclusion: Because of adequate surgical anesthesia, intraoperative hemodynamic stability and prolonged post-operative analgesia, we recommend the use of intrathecal Pentazocine as a sole anesthetic agent for lower segment caesarean sections.
Authors and Affiliations
Selvakumaran P, Anand B, Thirumaaran U G
Keywords
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- EP ID EP521046
- DOI 10.26611/10159211
- Views 187
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