A Comparative Study to Evaluate the Effects of Nitroglycerin and Esmolol on Haemodynamic Parameters in Controlled Hypertensive Patients During Emergence From Anaesthesia and Extubation
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 3
Abstract
Introduction: Tracheal extubation is performed when the patient is in lighter stages of anaesthesia, which produces significant increase in heart rate & arterial pressure. These changes in physiology are a matter of concern in Hypertensive patients. So our aim was to compare the effects of Nitroglycerin & Esmolol on haemodynamic parameters in controlled hypertensive patients during emergence from anaesthesia & extubation. Material & Methods: The patients were randomly divided into two groups Group I (NTG group) (n=30): received nitroglycerin 0.5μg/kg/min, IV infusion Group II (Esmoolol group) (n=30): received Esmolol 100 μg/kg/min, IV infusion. Observations: Administration of Nitroglycerin & Esmolol in controlled hypertensive patients during emergence from anaesthesia & extubation in ASA gr II & III pts helps in controlling hypertension. However Esmolol has better control on heart rate & thus on Rate pressure product. Conclusion: Esmolol is better than NTG in controlling the haemodynamic parameters during extubation in controlled hypertensive patients, where rate pressure product is important predictor of complications (myocardial ischaemia).
Authors and Affiliations
R. Vachhani, Rahul Gulati
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