A Comparison of Analgesic Effects of Clonidine with Ropivacaine and Dexmedetomidine with Ropivacaine for Caudal Analgesia in Children Undergoing Lower Abdominal Surgeries
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
Introduction: Pain is an unpleasant subjective sensation which can only be experienced and not expressed, especially in children. The concept of postoperative pain relief and its utilization in the pediatric age group has improved dramatically over the recent years. Materials and Methods: The study was approved by institutional ethics committee and 60 patients with 30 in each group were included in this study. 60 patients were divided into two groups alternatively. Group C (n=30): Patientswill receive 1ml/kg of 0.2% ropivacaine and 1µg/kg of clonidine (making a volume of 0.5ml with addition of 0.9% saline using a tuberculin syringe). Group D (n=30): Patients will receive 1ml/kg of 0.2% ropivacaine and 1µg/kg of dexmedetomidine (making a volume of 0.5ml with addition of 0.9% saline using a tuberculin syringe). Results: Present clinical study consists of 60 patients, aged between 1to 8 years, who are randomly chosen and divided into two groups alternatively into Group C and Group D which received the respective study solutions. Present clinical study was conducted on ASA Grade I and II pediatric patients who were undergoing infraumbilical (herniotomy, circumcision, high ligation of sac and rectal polypectomy) surgical procedures, at Kamineni Institute of Medical Sciences, Narketpally, Nalgonda district, Telangana. Conclusion: Dexmedetomidine 1μg/kg and Clonidine 1μg/kg appear to be satisfactory adjuncts to ropivacaine, which produced satisfactory intraoperative analgesia and also satisfactory postoperative analgesia. Dexmedetomidine 1μg/kg as an adjunct to 0.2% ropivacaine produced statistically significantprolonged duration of postoperative analgesia when compared to Clonidine 1μg/kg as an adjunct to0.2% ropivacaine. In both thegroups intraoperative parameters i.e heart rate, mean arterial pressure and oxygen saturation was maintained throughout the surgery and did not differ significantly from the preoperative baseline values. Also there was no significant difference in themean heart rates, mean arterial pressure and oxygen saturation between the two groups. There was no significant difference between the mean sedation scores. There were no significant complications in the postoperative period in both the groups.
Authors and Affiliations
Dr. Rajeshwari D, Dr. Rajashekar Reddy B
Keywords
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- EP ID EP558134
- DOI 10.9790/0853-1803167384.
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