A COMPREHENSIVE REVIEW ON EXTENDED RELEASE FORMULATIONS
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2012, Vol 2, Issue 4
Abstract
Oral drug delivery is the most preferred route of drug administration. Hydrophilic matrices are widely used platform for oral extended release drug delivery around the globe and most extensively studied. This is due to their broad regulatory acceptance, relative ease of formulation and manufacturing and historical commercial success in the market place. The use of extended release products offers some potential advantages in patient convenience/compliance and therapeutic outcomes. However, the range of drugs for which clinically significant advantages have been shown is limited. Prescribers and pharmacists should be aware of the costs of these products and have knowledge of their clinical use in selected patient groups. In some instances, the formulation is probably serving a marketing objective rather than a clinical objective. This article will review the importance of the extended release drug delivery system and critical formulation aspects of hydrophilic matrix technology with emphasis on the influence of polymers on their release performance.
Authors and Affiliations
Soma Sekhar K, Dr. M. V. Nagabhushanam
Keywords
Related Articles
- EP ID EP223280
- DOI -
- Views 131
- Downloads 0
FORMULATION AND EVALUATION OF EFFERVESCENT TABLETS OF TRIPHALA CHURNA
Abstract The present research work is based on the formulation of effervescent tablets. In the present investigation various standardization parameters such as physicochemical parameters like weight variation test, hardn...
EFFECT OF FORMULATION EXCIPIENTS ON AEROSOLISATION PERFORMANCE OF BUDESONIDE
The marketed dry powder inhalations (DPI) are based on lactose monohydrate alone and lactose anhydrous is neither studied nor used as a carrier in marketed DPIs. Lactose is not recommended as a carrier in budesonide form...
SELECTIVE AND SENSITIVE RP-HPLC METHOD FOR THE ESTIMATION OF TACROLIMUS IN CAPSULE DOSAGE FORM
Abstrac Tacrolimus is used as an immunosuppressant. The method developed is used for assay tacrolimus in pharmaceutical dosage form. A simple, rapid and reproducible high performance reverse phase liquid chromatographic...
COMPARATIVE STUDY AND ANALYSIS OF RELEASE KINETICS OF CORIANDER FORMULATIONS
Acne is an inflammatory disease of sebaceous follicles of skin. The present study was conducted to formulate and evaluate the topical anti acne formulation of coriander oil and coriander aqueous extract with and without...
NANOSPONGES: A BOON TO FIELD OF PHARMACY
Abstract Effective targeted drug delivery systems have been a dream for long time. The invention of nanosponges has become a significant step towards overcoming these problems. These small sponges can circulate around th...