A COMPREHENSIVE REVIEW ON FUTURE PROSPECTS FOR FAST DISSOLVING ORAL FILMS
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2012, Vol 2, Issue 4
Abstract
The ultimate goal of any drug delivery system is the successful delivery of the drug to the body, however patient compliance must not be overlooked. Oral drug delivery is the most widely utilized route of administration among the entire route that has been explored for the systemic delivery of drug via various pharmaceutical products of different dosage forms. With conventional tablet dosage forms, poor patient compliance can be observed especially in case of paediatrics and geriatrics patients, who experience difficulties in swallowing. In response to this mouth dissolving drug delivery system (MDDs) was developed as an alternative to the tablets & capsules. Mouth dissolving films (MDF) are the novel dosage forms that disintegrate and dissolve rapidly within the oral cavity. Intra-oral absorption permits rapid onset of action and helps by-pass first-pass effects, thereby reducing the unit dose required to produce desired therapeutic effect. The present review provides an overview of recent advancements, manufacturing methods and various polymers used in the manufacture of mouth dissolving film.
Authors and Affiliations
Kishore kumar. S, Dr. M. V. Nagabhushanam
Keywords
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