A comprehensive review on pharmaceutical mini tablets
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2018, Vol 8, Issue 6
Abstract
Mini-tablets represent a new trend in solid dosage form design, with the main goal of overcoming some therapeutic obstacles. Mini tablets are multiple unit dosage forms and are advantageous than pellets or any other oral dosage forms as they are easy to manufacture and stability problems are less. Offering some therapeutic benefits such as dose flexibility and combined release patterns. They do not require any solvent for their production and also local irritation can be avoided by the use of mini tablet Mini tablet offer several advantages like they can be manufactured relatively easily, They are not require less coating materials and also there is a great flexibility during their formulation development. Mini tablet are more acceptable in children and elderly people as they are easy to swallow. The objective of controlled drug delivery systems is to reduce the frequency of the dosing and to increase the effectiveness of the drug by localization.
INNOVATIVE AND NOVEL STRATEGY: MICROSPONGES FOR TOPICAL DRUG DELIVERY
Microsponge type of drug delivery is the latest technology which has been introduced in topical skin care, drug products to facilitate the controlled release of the active medicament into the skin in order to reduce syst...
ANTI-DIABETIC POTENTIAL OF AQUEOUS, METHANOLIC AND SAPONIN EXTRACT OF LEAVES OF ZIZIPHUS NUMMLARIA LINN.
The aqueous and methanolic extract of the leaves of Zizyphus nummularia were obtained from successive solvent extraction. The methanolic extract was further solvent extracted with water saturated n-butanol solvent and or...
Formulation development and optimization of fast dissolving film containing carvedilol nanocrystals for improved bioavailability
In this work, fast dissolving films (FDF) were prepared using nanocrystal formulations in order to optimise dissolution properties of lipophilic, poorly soluble drug Cavedilol. Drug nanocrystals are crystals with a size...
PHYTOCHEMICAL ANALYSIS AND EVALUATION OF SCAVENGING ACTIVITY OF METHANOLIC EXTRACT OF ADENANTHERA PAVONINA LINN LEAVES
Aim: Reactive oxygen species (ROS) such as superoxide anion, hydrogen peroxide and hydroxyl radicals are involved in the oxidative damages resulting in pathogenesis of the various disorders and diseases. Thus, the scaven...
HEPATOPROTECTIVE ACTIVITY OF CHENOPODIUM ALBUM LEAVES EXTRACT IN CCl4 INDUCED HEPATOTOXICITY IN RATS
Objective- Hepatoprotective activity of Chenopodium album leaves extract in CCl4 induced hepatotoxicity in rats. Method- The present study has been undertaken to evaluate hepatoprotective activity of Chenopodium album l...