A drink containing amino acids and chromium picolinate improves postprandial glycemia at breakfast in healthy, overweight subjects
Journal Title: Functional Foods in Health and Disease - Year 2017, Vol 7, Issue 2
Abstract
Background: Chromium (Cr) and certain amino acids (AA) have individually shown to improve postprandial glycemia. Method: The present randomized, controlled, cross-over trial in 19 healthy, overweight subjects (age 51±1y and BMI 27.3±0.3 kg/m2; mean±SEM) evaluated a combination of leucine, isoleucine, valine, lysine and threonine (5AA) with Cr. Postprandial glycemia and insulinemia were measured following a bread meal, served with carbonated water (Ref) or carbonated water containing 5AA, Cr-picolinate (CrPic) or a combination (5AA+CrPic). Results: The 5AA+CrPic and 5AA, respectively, lowered the incremental glucose peak (P< 0.001) by almost 30% compared to Ref. No significant differences in incremental insulin peaks were found but, during the first 15 min, 5AA induced a higher insulin response (+112%; p<0.01) compared to Ref. Interestingly, 5AA+CrPic reduced the initial AA-induced insulin increase by more than 50%, indicating improved insulin economy. Conclusions: These observations suggest that a drink containing both 5AA and CrPic attenuate postprandial glycemia in healthy “at risk” subjects.
Authors and Affiliations
Elin Ostman, Anna Forslund, Rickard Oste, Inger Bjorck
Keywords
Related Articles
- EP ID EP435089
- DOI 10.31989/ffhd.v7i2.304
- Views 186
- Downloads 0
Effects of vitamin E and its derivatives on diabetic nephropathy in Rats and identification of diacylglycerol kinase subtype involved in the improvement of diabetic nephropathy
Background: Diabetes is a significant social issue. Controlling diabetic complications such as nephropathy is very important for QOL of diabetic patients. One of the mechanisms which causes diabetic complications is the...
The influence of probiotics on individual fecal secondary bile acid levels: a two-case study of schizophrenic patients receiving an atypical antipsychotic drug
Background: Probiotics is used as a promising approach in the prevention and treatment of hypercholesterolemia. Modification of bile acid metabolism through the deconjugation of bile salts by microbial bile salt hydrolas...
Use of lysozyme from chicken egg white as a nitrite replacer in an Italian-type chicken sausage
Background: Sodium or potassium nitrite is widely used as a curing agent in sausages and other cured meat products. Nitrite has strong antimicrobial and antioxidant effects and generates cured meat color. Nitrite, howeve...
Immunological effects of Kefir produced from Kefir grains versus starter cultures when fed to mice
Background: Natural kefir grains have a unique microbiota. The structure contains lactic acid bacteria (LAB), acetic acid bacteria and yeast in specific ratios in a polysaccharide matrix. Authentic kefir is produced by a...
Improvement of glucose metabolism via mung bean protein consumption: A clinical trial of GLUCODIATM isolated mung bean protein in Japan
Background: The main component of mung bean protein, accounting for more than 80%, is 8Sα globulin. Its structure closely resembles that of soybean β-conglycinin. Thereby, the mung bean protein is expected to have simila...