A health care-associated pneumonia case due to colistin resistant Acinetobacter baumannii
Journal Title: Journal of Microbiology and Infectious Diseases - Year 2014, Vol 4, Issue 3
Abstract
A 78 year old male was hospitalized in neurology clinic with a diagnosis of encephalopathy. On 13th day of imipenem treatment for ventilator-associated pneumonia (VAP), a new VAP episode was diagnosed based on physical examination, laboratory and radiological findings. Cefoperazone-sulbactam 2x2 gr/day IV was started empirically. In the 3rd day of treatment Acinetobacter baumannii was identified from endotracheal aspirate culture that was resistant to all other antibiotics including colistin except cefoperazone-sulbactam (intermediate) and tigecycline (MIC: 4 mg/L, intermediate) by VITEK and E-test. Tigecycline 2 x 50 mg (after loading dose of 100 mg) IV, colistin IV 2 x 150 mg and colistin inhaler 2 x 75 mg were added to the cefoperazone-sulbactam 2 x 2 gr IV. Clinical findings were improved under this combination and completed to 14 days. The patient was discharged from hospital with neurological sequel after three months. This case has been presented to emphasize that colistin resistant Acinetobacter baumannii is becoming a problem for our country. J Microbiol Infect Dis 2014; 4(3): 111-113 Key words: Acinetobacter baumannii, colistin resistant, pneumonia, multidrug resistant
Authors and Affiliations
Siran Keske, Gül Yılmaz, Tümer Güven, Rahmet Güner, Mehmet Taşyaran
Keywords
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- EP ID EP121685
- DOI 10.5799/ahinjs.02.2014.03.0150
- Views 140
- Downloads 0
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