A histopathological study of neoplastic and non-neoplastic breast lesions
Journal Title: Medpulse International Journal of Pathology - Year 2019, Vol 9, Issue 1
Abstract
Background: The female breast is one of the most commonly biopsied tissues because of the myriads of diseases and lesions that arise from it. Timely and accurate diagnosis of a breast lump can not only alleviate anxiety but also early intervention can be lifesaving. In India, breast cancer forms the second most common malignancy after cervical cancer and is detected in 20/1,00,000 women. Objectives: To study the clinic pathological aspect and histopathological patterns of neoplastic and non neoplastic breast lesions. Material and Method: A prospective study was carried out on 218 cases in tertiary care institute at S.R.T.R. GMC Ambajogai. Breast lesions were evaluated over a period of one and half year. The specimen were routinely processed and stained with Heamatoxylin and Eosin (HandE) and examined microscopically. Cases included in this study were of non-neoplastic and neoplastic breast lesions which included incisional biopsies, lumpectomy and all types of mastectomy specimens from surgical department at rural hospital. Results: Among 218 cases, 181 were neoplastic and 37 cases were non neoplastic. Majority of cases were fibroadenoma i.e. 118 cases. Invasive carcinoma -no special type (NST) was the most common malignant neoplasm i.e. 43 cases. The most common inflammatory nonneoplastic lesion was mastitis with 14 cases and benign epithelial lesion was fibrocystic change. Most of the breast tumors were noted in left breast and involved upper outer quadrant most frequently.The nonneoplastic lesions were common in third decade, benign tumour in second and third decades and malignant tumours were common in sixth decades. Conclusions: This study highlights the importance of histopathological examination in breast lumps not only in establishing the final diagnosis, but also in predicting the prognosis of breast neoplasms.
Authors and Affiliations
Sheela L Gaikwad, Apurva A Bhure, Sandhya B Narwade
Keywords
Related Articles
- EP ID EP456319
- DOI 10.26611/105911
- Views 81
- Downloads 0
Etiology, clinical presentation and diagnosis of different types of anemia in pediatric age group: A prospective study
Background: Anemia can be defined as a hemoglobin level less than the 5th percentile for the particular age. Anemia is not a disease in itself but is indicative of underlying iron deficiency or more sinister pathologies...
Distribution of ABO and Rhesus blood groups in blood donors at blood bank of tertiary care hospital, Mahabubnagar, Telangana
Background: Blood groups of population are determined genetically by the presence of specific antigens on the erythrocytes (Red blood cells). Blood group antigens are inherited in a mendelian fashion and appear early in...
Clinico-pathological study of male breast lesions
Background: Male breast lesions are less common than female breast lesions, which include non-neoplastic inflammatory, benign and malignant neoplastic lesions. Aim: To study the clinico-pathological characteristics of br...
Evaluation of sickling and solubility tests and peripheral blood smear method for screening of sickle cell disease
There are various tests like sickling, solubility and peripheral blood film methods for the screening of sickle cell disease but their reliability and ease of applicability has not yet been determined. Hence this study h...
A cross sectional analysis of anemia in paediatric population in a tertiary care hospital, Madurai
Background: It is an axiomatic truth that children of today are citizens of tomorrow and upon them depend the weal and welfare of the community. In a country like India, children fall an easy prey to anemia as majority o...