A histopathological study of smoking on free gingiva in patients with moderate to severe periodontitis
Journal Title: Caspian Journal of Dental Research - Year 2013, Vol 2, Issue 1
Abstract
Introduction Cigarette smoking has been recognized to be a risk factor for progression of periodontal disease. Due to less inflammation and bleeding in the presence of clinical signs of periodontal disease in smokers than in nonsmokers and given the conflicting results of studies on changes in the epithelium and gingival connective tissue by smoking, this study was performed to evaluate the thickness and keratosis on the epithelium of free and sulcular gingival tissue in smokers and nonsmokers patients with moderate to advanced periodontitis. Methods: In this cross sectional study, biopsies were obtained from palatal gingival of 60 patients with moderate to advanced periodontitis (30 smokers and 30 nonsmokers). These biopsies were histologically processed, serially sectioned at 5 microns, stained with H. E. and examined by image analysis software (analysis-SL-starter), which was used to perform the morphometric evaluation of the outer and inner epithelial thickness, keratosis and vascularity in connective tissue. The data were analyzed with SPSS 17, t-test, Mann-Whitney Test, and Pearson correlation. p<0.05 was considered significant. Results: Histopathological examination showed significant association between smoking and CAL (p=0.048), keratosis on outer epithelium (p=0.020) and mean of thickness of outer (p=0.023) and inner (p<0.001) marginal gingival epithelium but gingival vascular density in nonsmokers was more than smokers (p=0.002). Collagenized connective tissue was observed in smokers more than nonsmokers. (p>0.001) Conclusions: It seems that the reduction of the clinical signs of inflammation in the gingival tissue of smokers is due to changes in gingival epithelium and connective tissue from smoking.
Authors and Affiliations
Maryam Seyedmajidi, Parand Keshavarzi, Ali Bijani, Reza Faraji, Neda Babaee
Keywords
Related Articles
- EP ID EP177746
- DOI -
- Views 114
- Downloads 0
Comparative evaluation of five different storage media and temperature effect on human periodontal ligament fibroblast viability
Introduction: Following dental avulsion, the immediate recommended treatment is tooth replantation to avoid adverse effects. Therefore, the tooth must be stored in a physiological storage medium to preserve the viability...
Evaluation of quality and quantity of solid wastes in Babol Dental Faculty–North of Iran
Introduction: Dental wastes are a main part of urban solid wastes in each society and have pathogenic agents and toxic chemicals, which put health of patients, personnel and other referees to dental clinics in danger. Th...
Frequency of oral cancer in Babol during 2012-2016
Introduction: Regarding the lack of data on the frequency of oral cancer in Babol, the aim of this study was to evaluate the frequency of oral cancer in Babol during 2012-2016. Material & Methods: This retrospective cro...
Vital pulp therapy with two different calcium-silicate cements: two cases report
It is a worthy aim to preserve the pulp vitality in teeth with immature root in order to continue the root's maturation. Traumatic injuries and caries are two main reasons for pulp exposure in immature teeth. This articl...
Plexiform schwannoma of the floor of the mouth: a case report
Plexiform schwannoma is a type of schwannoma that can be occured at any age and any site of the oral cavity. In the gross and histopathological features, it shows plexiform or multinodular growth pattern. This variant of...