A Histopathological Study of the Small Intestinal Lesions
Journal Title: National Journal of Laboratory Medicine - Year 2017, Vol 6, Issue 2
Abstract
Introduction: Frequently received specimens of small intestine are non neoplastic diseases like Crohn’s, ischemic enteritis, non-specific enteritis, tuberculosis and neoplastic diseases like adenomas and carcinomas. Clinical and radiological findings are non specific and histopathological study is required for the diagnosis. Aim: To study histomorphology of small intestinal lesions and analyze with respect to age, sex, anatomical site of occurrence and relative frequency. Materials and Methods: This study of 124 cases was undertaken in the Department of Pathology, JSS Medical College and Hospital, Mysuru, India, between 2009 to 2012. In addition to H and E, Immunohistochemistry and special stains were done in required cases. Results: Total 124 cases of small intestinal lesions including the periampullary lesions were studied. Of these, 71 cases (57.25%) were non neoplastic and 53 cases (42.75%) were neoplastic. Common age group was 5th-6th decade. A male preponderance was observed. Most common non neoplastic lesions were non-specific enteritis (52.11%) and enteric fever (40%). Amongst neoplastic lesions, total 45 (84.91%) cases were malignant comprising adenocarcinomas of the periampullary region (49.06%) and carcinoid tumours (11.32%). Benign lesions were adenomas. Rare cases like myeloid sarcoma, metastatic adenocarcinoma and metastatic malignant melanoma were observed. Conclusion: A greater awareness of various diseases affecting the small intestine and an understanding of the pathogenesis on the part of the pathologist is felt necessary for a better diagnosis. A detailed histopathological study of the small intestinal specimens should be done in constant correlation with the clinical and radiological findings for an accurate diagnosis.
Authors and Affiliations
Guru Raja Prasad Chennakeshaviah, Dharani Vitalapura Cheluvegowda, Ranga Swamy Maggad, Manjunath Gubbanna Vimalambika
Keywords
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- EP ID EP376451
- DOI 10.7860/NJLM/2017/24952:2217
- Views 112
- Downloads 0
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