A methodological exploration of bioactive components of the traditional Chinese medicines guided by in vivo absorption and distribution characters of the constituents
Journal Title: Science Paper Online - Year 2006, Vol 1, Issue 4
Abstract
By using a Tibetan herbal medicine Halenia elliptica L. (a liver protect remedy) as an example, a method to investigate bioactive components of the traditional Chinese medicines (TCM), under a guidance of in vivo absorption and distribution characters of the chemical constituents of TCM, was explored. The in vivo absorption and distribution characters of the chemical constituents of TCM were determined by HPLC-DAD-ESIMS, 8 chemical constituents of H. elliptica that are absorbed and distributed organs and tissues of mice were isolated and identified. Several constituents showed antioxidant, liver-protect, and cytotoxic activities in the in vitro assays. This study indicated that the explored method is feasible, and valuable.
Authors and Affiliations
Jie Gao, Sujuan Wang, Ruiming Xu
Keywords
Related Articles
- EP ID EP144572
- DOI -
- Views 123
- Downloads 0
Measurement of Triglyceride Content of Resin in Masson Pulp by UV Spectral Method <br /> <br />
Pitch deposite is one of the most troublesome problems for the paper mills in South China that use the Masson pine as a raw material to make paper. The triglyceride has been identified as the main compositions accounting...
微合金化洁净车轮钢产生氢鼓泡的 可扩散氢临界质量分数
用电解充氢法研究了微合金化洁净车轮钢产生氢鼓泡的可扩散氢临界质量分数。结果表明，洁净车轮钢的可扩散氢质量分数随充氢电流密度的增加而增加，氢鼓泡密度也随着充氢电流密度的增加而增加，试样中产生氢鼓泡的可扩散氢最低质量分数为2....
磁流化床铁基选择性催化还原烟气脱硝
本文介绍近年来铁离子交换沸石催化剂、氧化铁催化剂等铁基催化剂选择性催化还原(SCR)脱硝的研究进展；分析磁流化床的特性，提出利用磁场流态化技术进行磁性颗粒催化还原脱除氮氧化物的新技术构思，并对此脱硝反应的机理及实验方案进行初...
流体介质中柔性平板振动的特征灵敏度分析
柔性结构在流体介质中振动，诱导流场对振动的影响不可忽略，分析结构振动特性的灵敏度也需要考虑诱导流场的影响。论文作者在偶极子配置法计算流场附加质量的基础上，利用灵敏度分析的直接法发展了一种考虑柔性平板在流体介质中振动的流固...
Design and application of automatic monitoring and controlling system for flotation column
The control requirements and the principle of flotation column were analyzed and elaborated emphatically. The design method of the multivariate inputs/multivariate outputs is adopted. The controx2000 configuration softwa...