A NEW NAPHTHOQUINONE ISOLATED FROM POLYGONUM MULTIFLORUM (POLYGONACEAE)
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2016, Vol 8, Issue 8
Abstract
Objective: This research is mainly focused towards isolation and structural elucidation of pure compounds from the extract and fractions of Polygonum multiflorum through silica gel column chromatography.Methods: The air dried rhizomes were extracted with Me2CO (acetone), MeOH (methanol) and H2O (water). The Me2CO extract was fractionated into CHCl3 (chloroform) and residue. The chloroform-soluble portion and MeOH extract were subjected to silica gel column chromatography for the isolation of pure compounds. The isolated compounds were then determined by the use of spectroscopic analysis of HRFABMS, 1H, 13C NMR, UV and IR spectra.Results: CHCl3 soluble portion of Me2CO and MeOH extract of P. multiflorum led to the isolation of one new naphthoquinone and eight known compounds including four anthraquinones, one naphthoquinone and two stilbenes.Conclusion: The obtained results will be very useful for the further evaluation various biological studies.
Authors and Affiliations
Mopur Vijaya Bhaskar Reddy
Keywords
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