A novel predictor in acute kidney injury: Neutrophil to lymphocyte count
Journal Title: Ege Tıp Dergisi - Year 2018, Vol 57, Issue 1
Abstract
Aim: Acute Kidney injury (AKI) represents a clinical condition reflecting systemic inflammation. Neutrophil-to-lymphocyte ratio (NLR) is novel prognostic marker in various inflammatory conditions. In this retrospective cohort we evaluated two hundred and thirteen AKI patients. Materials and Methods: The patients’ baseline values on admission, final values at discharge and after discharging during follow-up period in outpatient clinic until six months to one year were recorded. NLR change during follow-up period after hospitalization was also examined. Results: It has been shown that, final NLR and timely changed NLR during hospital course are significant mortality predictors in AKI patients both in univariate and mutually adjusted multivariate logistic regression analysis. To predict mortality, we showed that, level of 9.90 point for final NLR has 73% sensitivity and 87% specifity as compared to value below in ROC analysis (HR: 7.31, CI 3.36-15.91; p<0.001). Conclusion: NLR may be a novel screening tool on patiens' mortality for AKI patients during their hospital course.
Authors and Affiliations
Devrim Bozkurt, Aslı Kılavuz, Mehmet Berktaş, Fehmi Akçiçek
Keywords
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