A Novel Sclerectomy Technique for Glaucoma and Ocular Hypertension Treatment
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 8, Issue 7
Abstract
Purpose: To introduce and evaluate the efficacy and safety of a new surgical scleral technique for treatment of glaucoma based on the concept of scleral biomechanics. Methods: Twelve 3-month-old New Zealand white rabbit eyes were operated under general anesthesia. Single large rectangular full thickness sclerectomy (3 mm limbal x 5 mm) exposing the choroid was performed in each eye. The intraocular pressure (IOP) was measured preoperatively, one day, one week and one month postoperatively. Results: Twelve eyes of 6 New Zealand white rabbits were operated with sector sclerectomy technique. The mean (±SD) intraocular pressure (IOP) was significantly reduced from a preoperative value of 6.0 (±0.0) mmHg to 2.0 (±0.0) mmHg (p = 0.003) in the post-operative assessment. The IOP was quite stable in the following one week and one month follow up assessments at 2.0 (±0.0) mmHg (p = 0.998). Eight out of 12 (66.7%) operated eyes had no postoperative complications. Four (33.3%) eyes faced different complications where: one (8.3%) had corneal perforation by traction suture, 3 (25%) had vitreous loss (one mild and two severe), while one of them (8.3%) had bleeding. Conclusion: Full thickness sector sclerectomy can change the scleral biomechanical behavior leading to highly significant intraocular pressure reduction.
Authors and Affiliations
Ahmed S. Elbably, Ehab Ahmed, Mohamed M. Abo-Zaed, Mohammed S. Elbably, Tag El-Din M. Othman, Ahmed Mousa
Keywords
Related Articles
- EP ID EP347400
- DOI 10.9734/BJMMR/2015/17207
- Views 54
- Downloads 0
Comparative Study of Artherogenic Effects of Common Nigerian Edible Oils in Male Rabbits
Aims: To compare the atherogenicity of edible oils namely, palm, groundnut and egusi melon oils in male rabbits by determining their lipid profile and presence of atherosclerosis in their aortas. Methodology: Twenty-fiv...
Morphometry of Human Fetal Ear Ossicles: A Human Cadaveric Study
Aim: Most of the studies were on adult ossicles. In this present work, the aim is to study the morphometry of the ear ossicles in the human fetuses and use of the study in medical applications. Materials and Methods: Thi...
Public Health Informatics: A Brief Review of the Field
In the global community of today, the importance of accessing timely and relevant information has increased in value. However, with the exponential increase in data and data sources, innovations to monitor, control, and...
Reproductive Hormonal Profile of Post-menopausal Women in Ebonyi State, Nigeria
Background: Assessment of the concentrations of reproductive hormones during post-menopause has been suggested as a confirmatory test for menopause due to irregularities in rise and fall of sex hormones in menopausal tra...
Association of Angiotensin-I-Converting Enzyme (ACE) Insertion/Deletion Gene Polymorphism with End Stage Renal Disease in Egyptian Patients
Angiotensin-I-converting enzyme (ACE) insertion/deletion (I/D) polymorphism has been associated with the genetic susceptibility to end stage renal disease (ESRD) in different populations. ACE DD genotype and D allele are...