A PREDICTIVE MODEL FOR ETHNOMEDICINAL DISCOVERY RESEARCH- A NIGERIAN CASE STUDY
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2014, Vol 3, Issue 6
Abstract
Using a model parametrically dependent on a number of research factors we have examined the relationship between ethnomedicinal drug discovery research in Nigeria and the goal of advancing drug candidates into preclinical evaluation. Our investigation covered a 13-year period and involves several ethnomedicinally relevant plant materials. The employed qualitative model utilizes model scores in assessing research quality and the chances to attain preclinical testing. Based on the model, the research methodologies were found to focus on highly rudimentary tools involving crude extraction, which the model indicated as a vital disadvantage. The existence of foreign collaborations as well as the number of such collaborations was found to improve model score and as extension the likelihood to generate candidates for drug development.
Authors and Affiliations
Olujide O. Olubiyi (Ph. D)| Department of Pharmacology & Therapeutics, College of Medicine & Health Sciences, Afe Babalola University, Ado-Ekiti, NIGERIA, Oloruntoba C. Akintayo (M. Sc)| Department of Physiology, College of Medicine & Health Sciences, Afe Babalola University, Ado-Ekiti, NIGERIA.
Keywords
Related Articles
- EP ID EP3445
- DOI -
- Views 339
- Downloads 16
Evaluation of Microbial Contamination of Eye Make up Product: Mascara
Eyes are one of the most important features when it comes to beauty. Various cosmetics are used to enhance their level of attractiveness like mascaras, eyeliners eye shadow among many more. Out of these above products ma...
Bioguided extraction and Evaluation of Antioxidant studies of Abutilon indicum fruits
The present study was conducted to evaluate the antioxidant activity, to determine the phytoconstituents, phenolic content and flavonoids in different fractions of Abutilon indicum fruits. The hydro alcoholic extract of...
SEROPOSTIVITY OF TRANSFUSTION TRANSMISSIBLE HIV INFECTIONS AMONG VOLUNTARY AND REPLACEMENT BLOOD DONORS
Background: The evaluation of the data of the prevalence of transfusion transmissible infections (TTI) among blood donors permits an assessment of the acqisition of the infections in the blood donor population and conseq...
THE POSSIBLE PROPHYLACTIC EFFECT OF EGYPTIAN MORINGA OLEIFERA SEED OIL AS ANTI-ULCER ACTIVITY AND ANTI-INFLAMMATORY IN RATS.
Moringa oleifera Lam. is the multipurpose tree (therapeutic potential and nutritive value). In this work, authors focused on importance of Moringa oleifera seed oil (MSO) as antioxidant, anti-inflammatory and antiulcer....
A REVIEW ON ACNE
Acne is a cutaneous pleomorphic disorder of the pilosebaceous unit involving abnormalities in sebum production and is characterized by both inflammatory (papules, pustules and nodules) and non inflammatory (comedones, op...