A Prospective Clinical Study of Congenital Heart Disease in Children with Consanguineous Marriages
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 4
Abstract
Objectives: 1. To study the incidence of Congenital Heart Disease in children born to consanguineously married parents. 2. To study the spectrum of Congenital Heart Disease in children born to consanguineously married parents. Material and Methods: The study was conducted on 305 consanguineously married parents’ children in Dept. of Paediatrics. Govt. General Hospital, Kakinada. from October.’2010 to September.’2011. Age Group selected for this study are 0-5 Years children 2nd Degree, 3rd Degree and 4th Degree consanguineous marriages are included in this study. Maternal gestational diabetes, maternal exposure to teratogenic drugs; Radiations etc. are excluded from the study. Results: Out of 305 children born to consanguineously married parents, 36 had congenital anomalies 11.8% of which 16 cases found Congenital Heart Diseases (5.2%) and 20 cases found other Congenital Diseases like Gastroschisis, Club Foot, Cleft lip, Polydactyly, etc (6.55%). The frequency of Acyanotic Heart Diseases are 13 (81.3%) and Cyanotic Congenital Heart Diseases are 3 (18.7%) in 16 cases of Congenital Heart Diseases. Spectrum of Heart Diseases diagnosed are VSD, Dextrocardia, TOF, Complex CHD, ASD, PDA, MR and DORV. Conclusion: The study suggests that children born to consanguineous parents are more likely to have congenital heart disease and other anomalies involving various systems. Congenital Heart Diseases found to be more common in children born to 2nd Degree congenital couple.
Authors and Affiliations
Dr. M. S. Raju
Keywords
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