A Prospective Cross-Sectional Study of Exudative Diabetic Retinopathy and Its Association with Serum Lipid Levels
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Purpose: This prospective cross sectional study awsa done to study the association of serum lipids and exudative diabetic retinopathy.Methods: This was across sectional study conducted in patients visiting the outdoorunit of Department of Ophthalmology ,Maharani Lakshmi Bai Medical College Jhansi out during the period of 19 months from March 2015 to September 2016. This study included patients with age above 40 years, with diabetes, which is defined as a fasting plasma glucose of more than or equal to 126 mg/dl or a 2-hour post glucose load plasma glucose of more than or equal to 200 mg/dl or a random plasma glucose of more than or equal to 200 mg/dl in the presence of symptoms of hyperglycemia ,and duration > 5 years.Patients were divided in two groups GroupA included patients .Results: Among 150 patients in our study, 70 (46.7%) patients were having exudative diabetic retinopathy with or without CSME. Rest 80(53.3%) patients were having diabetic retinopathy without hard exudates or had no diabetic retinopathy Comparision between mean cholesterol in study group Group A 223.31 ± 51.20 and Group B 185.21 ± 30.02 showed p value <0.05 which was stastically significant. There was significant difference between mean triglyceride value in study group Group A (163.62 ±26.21) and in Group B w( 135.29 ± 22.12),mean LDL cholesterol in group A (151.23 ± 27.12 mg/dl )and in group B, (125.20 ± 22.22 mg/dl) and mean HDL cholesterol in group A (38.21 ± 5.20 mg/dl) and in group B (46.25 ± 6.75 mg/dl). No statistically significant difference was found on comparison of mean values of VLDL cholesterol in two groupsConclusions: The present study suggests that serum cholesterol, LDL, Triglycerides and low HDL levels have a significant and independent effect on retinal hard exudates.
Authors and Affiliations
Dr. Jitendra Kumar, Dr. Preeti Chaubey
Keywords
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- EP ID EP375970
- DOI 10.9790/0853-1706053741.
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