A prospective observational study of drug usage in paediatric inpatients at district teaching hospital
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2017, Vol 4, Issue 4
Abstract
Introduction: Aim of our study was to observe and analyse the prescribing pattern of drugs in hospitalised patients of paediatric department. Materials and Methods: A prospective observational study was conducted over a period of one year, after getting approval from Institutional Ethics committee. A specially designed proforma was used to collect the data from inpatients of paediatric ward of a tertiary care hospital. Inpatients with age group of 0 – 14 years were included in the study. Results: Out of 1050 patients, 471 were below the age group of one year, 220 patients were between 1-5 years and 359 patients were above the age of 5 years. The percentage of patients with antibiotic prescribed was 92.1%. Among the antibiotics, amikacin (483) was most commonly prescribed followed by cefotaxime (414) and ceftriaxone (301). Paracetamol was used as analgesic and antipyretic (45.5%) in the majority of the patients. The average number of drugs prescribed per patient was 5.7. In the majority of patients parenteral formulations were used either in the form of antibiotics or IV fluids (98.2%). Out of 96 different drugs, 57 (59.3%) drugs were prescribed by generic name. About 58.3% of drugs were prescribed from Essential Medicines WHO Model List (2015). Conclusion: Drug utilization studies are powerful exploratory tools to ascertain the role of drugs in society and create sound socio-medical and health economic basis for health care decision making. Continuous medical education with a focus on rational drug use and evidence based medicine should form part of the program in the hospital.
Authors and Affiliations
Rajeshwari . , Nagarajaiah B. H, Thamanna P. S, Drupad H. S
Phytochemical and pharmacological review on Cissampelospareira
According to a world health organization survey, about 75-80% of the world’s population relies on non-conventional medicine, mainly of herbal source, in their primary health care. In the past few decades, a massive amoun...
Knowledge and attitude of MBBS undergraduate students for use of generic medicines at a tertiary care hospital
Introduction The cost incurred on medicine is one of the major concerning components of health expenditure Prescription of generic drugs can reduce the costs without reducing the quality of treatment Hence this study is...
Plasma olanzapine concentration: Relation with dose, adherence to medication, and clinical efficacy
Objective To estimate plasma olanzapine concentration POC using liquid chromatographymass spectrometry LCMS and identify factors that contributes to pharmacokinetic variability of olanzapineMaterials and Methods This was...
Phytochemical and In-Vitro Evaluation of Antioxidant Activity of Sesamum Indicum Leaves
Objective: The aim of the present study was to evaluate preliminary phytochemicals and in-vitro evaluation of antioxidant activity of Sesamum indicum leaves. Methods: Antioxidant activity was evaluated by using in-vitro...
Development and Validation of RP-HPLC Method for Simultaneous Estimation of Paracetamol and Tramadol Hydrochloride
A simple and rapid RP-HPLC method has been developed for the simultaneous estimation of paracetamol and tramadol hydrochloride. The chromatographic analysis was carried out on an Enable C18 column (250×4.6 mm i.d., 5µm)...