A prospective, randomized, double blind, systemic controlled trial to compare analgesic efficacy of clonidine and fentanyl in supraclavicular block with 0.75% ropivacaine
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 4
Abstract
Introduction and Object Fentanyl and clonidine mostly used as adjuvant to improve quality and duration of nerve block In present study we compared clonidine and fentanyl perineurally and systemically in Supraclavicular Brachial plexus blockMaterials and Methods Sixty eight patients were randomly assigned into four equal groups scheduled for upper limb surgery They received the drugs in Supraclavicular block and intravenous route as below Group A 24 ml 075 ropivacaine 1 ml fentanyl 50gml 5ml normal saline in block and 1ml normal saline intravenously Group B 24 ml 075 ropivacaine 6ml normal saline in block and 1ml fentanyl 50g ml intravenously Group C 24 ml 075 ropivacaine 1ml clonidine 150gml 5ml normal saline in block and 1ml normal saline intravenously Group D 24ml 075 ropivacaine 6ml normal saline in block and 1ml clonidine 150gml intravenouslyResults Onset of sensory and motor block was significantly earlier in Group C 1247257 min 1800346 min than in Group A 1465341 min 1994261 min respectively p005 between Group A 741094hrs and Group B 735093hrs while it was prolonged in Group C 894097 hrs than Group D 812122 hrs pConclusion Fentanyl perineurally or systemically administered have comparable results while perineural clonidine offered prolonged duration of analgesia better than when it was used intravenously suggesting its local actionKeywords Supraclavicular Block Ropivacaine Clonidine Fentanyl
Authors and Affiliations
Garima Tyagi, Muni Ram Meena, Hemraj Tungria, Anisha Banu, Lalit Kumar Raiger
Keywords
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- EP ID EP476499
- DOI 10.18231/2394-4994.2018.0099
- Views 87
- Downloads 0
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