A prospective study of extent of hepatic involvement in patients of dengue infection presenting at a tertiary care hospital in rohilkhand region
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH - Year 2015, Vol 7, Issue 5
Abstract
Dengue is one of the most commonly occurring epidemic, particularly in rohilkhand region of Uttar Pradesh. The clinical manifestation ranges from being asymptomatic (in upto 80% patients) to mild illness (fever, thrombocytopenia, hepatic/renal dysfunction) to severe form (DHF/DSS – dengue haemorrhagic syndrome/dengue shock syndrome, DIC, MODS). Also it has been observed that the clinical and biochemical profile of dengue infection varies from epidemic to epidemic. We in this prospective study aim to study the epidemiological pattern, clinical profile and incidence and extent of hepatic complications in cases of Dengue fever in patients admitted at SRMS-IMS, Bareilly. We found that males were predominantly affected (73.3%). Most patients belonged to 15-45yr age group (85.5%). The incidence of DF, DHF, DSS were 64.4%, 26.7% and 8.9% respectively. Fever (100%) followed by headache (68.8%) was most common symptom. Malena (17.8%) followed by petechial rash (12.2%) and hematuria (3.3%) was most common hemorrhagic manifestation. Thrombocytopenia (platelet < 1lac/mm3) was present in 79% of patients. IgM antibody positive was seen in 40% patients and IgM was weekly positive in 15.5% patients. Raised bilirubin was present in 28.9% patients. Raised SGOT, raised SGPT, raised PT and raised APTT was present in 62.2%, 68.9%, 83.4% and 90% patients respectively. The most common finding on abdominal ultrasonography was ascitis (24.4%) followed by pleural effusion (18.9%), splenomegaly (14.4%) and hepatomegaly (6.6%).
Authors and Affiliations
Mowar, A. B. , Smita, G. , -, Himanshu, V. , Ashita, M. , Mirinda, J.
Keywords
Related Articles
- EP ID EP405555
- DOI -
- Views 119
- Downloads 0
An exploration on cytotoxicity induced by tobacco products and Cyto-protective effects of certain plant extracts
Cytotoxic effect of tobacco both in vivo and in vitro is confirmed by a wealth of scientific evidences available in literature. It is established that smokeless tobacco related tissue damage is related to reactive oxygen...
Respiratory-aspirated 50*15mm river shimp successfully cliped by virtual bronchoscope with foreign body forceps and avoiding the need for a thoracotomy
Respiratory Foreign body Aspiration (FBA) is a suddently life-threatening emergency. But, it is a seldom elaborated in textbooks. The most common site for that is the right low bronchus or its bronchus intermedius as it...
Management of dengue fever through ayurveda: A single case study
Dengue is considered globally as the most concerning mosquito borne arboviral disease in terms of morbidity and mortality that places a significant socioeconomic and disease burden on many tropical and subtropical region...
Comparative evaluation of blood culture, estimation of immunoglobulin m (igm) and c-reactive protein (crp) detection in the diagnosis of neonatal sepsis
This clinical study was conducted to evaluate the diagnostic value of C-reactive protein (CRP), Immunoglobulin M (IgM) in the early diagnosis of neonatal sepsis. The diagnostic values of each marker separately or in comb...
Caring for relatives with dementia in chinese family setting: the daughter-in-law
Introduction: The traditional role of filial care for frail elderly in Chinese family, the responsibility of caring has typically fallen on women, especially on the daughters-in-law (DILs). To date, little is known about...