A Prospective Study of Safety and Efficacy of Thalidomide in Dermatology in a Tertiary care centre - Tamilnadu
Journal Title: Stanley Medical Journal - Year 2017, Vol 4, Issue 1
Abstract
Context: Thalidomide can be safely and effectively used in the treatment of Erythema Nodosum Leprosum(ENL), Pyoderma gangrenosum(PG),Discoid Lupus Erythematosus(DLE).Aims: The use of thalidomide in relation to dermatology is well- known. Enough data is available in the literature about various aspects of thalidomide. Our study aims to assess the safety and efficacy of Thalidomide in patients with ENL, PG, DLE and psoriasis who were refractory to conventional treatment.Settings and Design:The study was done in the Dermatology Department, Govt. Stanley medical college hospital using a prospective study design.Methods and Material: The study was an open label, prospective interventional study. The Study population included 20 patients each of ENL, Pyoderma gangrenosum, psoriasis and 10 DLE patients. Inclusion and Exclusion criteria were fulfilled.Statistical analysis used: nil Results: The response to thalidomide was excellent in 3 of the 4 conditions we studied. Our study implies that Thalidomide can be safely and effectively used in the treatment of ENL, Pyoderma gangrenosum, DLE, though the clinical response to treatment in Psoriasis is not much satisfactory.Conclusions:Thalidomide with its excellent tolerability can be used for many dermatological conditions as an alternative when other modalities are contraindicated or ineffective. Key Messages: Thalidomide is safe and effective
Authors and Affiliations
Senthil Kumar V, Afthab Jameela Wahab . , Anandan V, Sivaranjani J
Keywords
Related Articles
- EP ID EP217392
- DOI -
- Views 124
- Downloads 0
FACTITIOUS DISORDER
Factitious disorder is characterized by knowingly repeated simulation of physical symptoms for the sole purpose of obtaining medical care and attention
A COMPARATIVE STUDY ON THE CONTRACEPTIVE METHODS PREFERRED IN RURAL AND URBAN AREAS IN TAMIL NADU
Introduction: Every fifth birth in the world is an Indian, and 50% percent of the Indian population are of reproductive age. There is still a large unmet need for contraception in India, and efforts to tackle the situati...
A Cross Sectional Study on Knowledge, Attitude and Practice of Cervical Cancer Screening Among Women in Thiruvanmiyur, Chennai
Aims: To assess the knowledge, attitude, practice and behaviour of cervical cancer screening, among women in Thiruvanmiyur, Chennai. Settings and Design: Cross sectional descriptive study Methods and Material: A cross se...
Management of Airway and ventilation during tracheal stenting procedure
Context: Management of Airway and ventilation for a surgery involving the airway is a challenge to the anaesthesiologists. Tracheal dilatation and stenting is a new procedure for treatment of subglottic stenosis. A 31 ye...
SYNDROMIC MANAGEMENT OF STD – IN THE CONTROL OF HIV
In India, the incidence of STDs is 4-5%, which accounts to 40 million cases per year. STDs can be treated either by aetiological or syndromic approach. Many countries are following syndromic approach which is based on...