A Prospective Study To Evaluate The Efficacy Of Probiotics In The Management Of Acute Watery Diarrhoea In Children
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 9
Abstract
Background: Diarrhoea is a leading cause of death in children, accounting for 9% of all deaths among children under age 5 worldwide in 2015.Treatment with ORS has reduced significantly the incidence of mortality and morbidity caused by diarrhoea. Probiotics are commonly used in the treatment and prevention of acute diarrhoea. Probiotics are live microbial feeding supplements that beneficially affect the host animal by improving its microbial balance. However, the clinical efficacy of probiotics in the treatment and prevention of acute infectious diarrhoea has not been fully established. Aim; The present study aimed to investigate the effects of probiotic consumption to decrease the severity and duration of diarrhoea in children aged 6 months to 5 years. -Method.: The study was conducted among children in age group of 6- 60 months of both genders admitted to hospital with acute diarrhoea.. Total 606(test=300, control=306) were enrolled, baseline hydration status was assessed and children were managed according to the WHO guidelines which included oral rehydration therapy (ORT) with reduced osmolarity ORS, zinc and continued feeding. Severe dehydration with intravenous fluids (ringer lactate) .Test group received Lactobacillus sporogenes in addition to the standard management of diarrhoea. primary outcome measures like duration of diarrhoea,change in stool consistency were analysed. Result: present study showed that children receiving Lactobacillus sporogenes along with ORS and Zinc had significant difference in the change in consistency and duration of hospital stay, while frequency and duration of diarrhoea didn’t differ much in both groups. Conclusion: Diarrhoea in most of the developing countries including India is usually self-limiting and does not require active treatment except replacement of fluids and electrolytes for prevention or correction of dehydration.This study confirms that L. sporogenes as probiotic in combination with ORS and zinc reduces the time for change in consistency of stools and duration of hospital stay while the frequency of stools and duration of diarrhoea didn’t differ significantly.
Authors and Affiliations
Dr. Shashikala Velampalli, Dr K. V. Subbarao
Keywords
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- EP ID EP395446
- DOI 10.9790/0853-1709094655.
- Views 50
- Downloads 0
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