A PROSPECTIVE STUDY TO FIND THE ASSOCIATION BETWEEN POOR POSTNATAL WEIGHT GAIN AND SEVERE RETINOPATHY OF PREMATURITY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 7
Abstract
BACKGROUND Retinopathy of Prematurity (ROP) is one of the leading causes of preventable childhood blindness in India, incidence is between 38 – 52% among low birth weight babies. With improved neonatal care and better survival rate of preterm infants, ROP incidence in our country is on the increasing trend. Identifying a modifiable postnatal risk factor like “poor postnatal weight gain” by simple serial postnatal weight measurements helps in identification of premature babies at risk for developing “severe ROP.” The aim of this study was to determine the association between poor “postnatal weight gain in babies” and incidence and severity of ROP. MATERIALS AND METHODS This was a prospective observational study, conducted over a period of 6 months at Govt. Rajaji Hospital, Madurai in 100 new born babies who fulfilled the inclusion exclusion criteria. The screening examination for ROP followed in our study was based on guidelines proposed by National Neonatology Forum (NNF). Relative weight gain is (Present weight - Birth weight) / (Birth weight x Chronological age in days) expressed in g/Kg/day. The data were analysed with SPSS statistical software package, Version 16.0 SPSS Inc., Chicago, USA). Sample size was taken conveniently. RESULTS Among the 100 babies studied, incidence of ROP was 38%. Incidence of severe ROP was 9%. In 9 cases with severe ROP, 2 were treated with intravitreal bevacizumab and laser photocoagulation while 7 were treated with only laser photocoagulation. 12 babies for whom extremes of relative weight gain was observed were excluded in statistical analysis for obtaining precise results and all were in Group 1. Relative weight gain (g/kg/day) in both the groups at second, fourth and sixth weeks of postnatal life was calculated as mean ±SD and were compared using unpaired student ‘t’ test at second, fourth and sixth week of postnatal life and all were found to be statistically significant with P-value of <0.0001. CONCLUSION The results of this study showed that “poor postnatal weight gain” in early postnatal period is a predictor for development of “severe ROP” requiring treatment with laser photocoagulation and/ or anti-VEGF in our hospital.
Authors and Affiliations
Karupputhevar Senthil, Sekar Soundharya, Ramanujam Balasubramanian, Jaganathansugumaran Rasigathivya, Shanmugam Aarti, Jayaraman Yavanarani, Padiraj Jayadurgadevi
Keywords
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- EP ID EP399116
- DOI 10.14260/jemds/2018/198
- Views 63
- Downloads 0
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