TOPICAL APPLICATION OF INSULIN IN THE DIABETIC WOUND ULCER OF FOOT AND ITS COMPARISON WITH REGULAR NORMAL SALINE DRESSING
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 95
Abstract
BACKGROUND Diabetic foot ulcers are inevitable in 15% of diabetic patients even if they follow the diet or control blood sugar level meticulously. The mainstay of treatment for diabetes related foot ulceration is a multidisciplinary team (MDT) approach that includes metabolic control, debridement, offloading/pressure redistribution, vascular control, infection control and seamless integrated wound care. And the ulcer usually is of a chronic type. With regard to topical agents, the effectiveness of topical Insulin is considered valid and effective on wound healing process. The present study is to compare the efficacy of Topical Insulin vs. Normal Saline dressing. MATERIALS AND METHODS This is a non-randomised control study. A total of sixty patients with Diabetic foot ulcer were enrolled and the study was done in Department of General Surgery, Sri Venkateshwaraa Medical College Hospital & Research Centre, Pondicherry from October 2015 to March 2017 for a period of 18 months. Patients were divided into two groups of 30 patients in each, Group A - topical insulin and Group B - normal saline. RESULTS The ulcer size on Day 1 was 48.33 ± 11.35 mm and 47.30 ± 11.30 mm in Insulin group and Saline group respectively, and the complete healing time achieved in Insulin Vs. Saline group was 30.63 ± 6.5 days and 60.47 ± 23.31 days respectively with significant p value <0.0001. CONCLUSION In the present study, 60 cases were studied comparing the wound dressing of the patient with topical insulin and the normal saline dressing in DFU. The use of topical insulin was found to be safe and effective in patients with diabetic foot ulcers. Results show that topically applied insulin can accelerate wound healing without any systemic side effects.
Authors and Affiliations
Rajesh Amal Praveen J, Naresh Kumar P
Keywords
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- EP ID EP280649
- DOI 10.14260/jemds/2017/1523
- Views 110
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