A Rare Case of Pediatric Systematic Lupus Erythematosus in Saudi Arabia
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 6
Abstract
Pediatric-onsetsystemic lupus erythematosus (SLE) is a rare disease. The skin is involved in up to 85% of the cases and may be the only organ involved in cutaneous lupus erythematosus. A two years and eleven months old boy presented with a one-day history of vomiting and diarrhea five to six times per day. His condition began at the age of 7 months with bilateral wrist joint swelling and pain with interphalangeal Joint swelling with ankle swelling and pain. This was associated with fever, macular rash. He was treated with steroids. Then with a recurrent history of fever, arthritis and the rash, Methotrexate and multi injections of tocilizumab for ten months were added. Then over this time, he developed recurrent otitis media and had recurrent mouth ulcers. His lab results showed inflammatory markers Anti-ds DNA were 23.7k/uL equivocal and ANA antibody is 12.1ng/mL which is positive. Brain MRI showed generalized atrophy with associated white matter changes. Findings could be related to the previous treatment or Periventricular leukomalacia or white matter diseases due to non-specific etiology. On discharge, he was afebrile for more than seven days, vitally stable, the rash was improved, and mouth ulcers also improved with good oral intake. He tried to walk, and joint swelling had decreased with no tenderness. In conclusion, although, childhood-onset SLE is rare, it should be suggested by clinicians in a differential diagnosis in a child with the suggestive clinical presentations as it has a greater risk of systemic complications in children.
Authors and Affiliations
Luai Mohammed Assaedi, Sahar Hasan Alsharif, Ali A. Alraddadi
Keywords
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- EP ID EP548828
- DOI 10.21276/ijmrp.2017.3.6.057
- Views 105
- Downloads 0
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