A Rare Case of Solitary Plexiform Neurofibroma of Tongue: A Case Report and Review of Literature
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 5
Abstract
The neurofibroma occurs as an isolated or multiple lesions frequently associated with neurofibromatosis type 1 (NF1)3 . A case of a sixty year old female with a solitary growth on the dorsum of tongue treated by total excision, diagnosed with plexiform neurofibroma based on immunohistochemistry marker S-100 is presented. She was having no other signs of any such lesions elsewhere in the body. Despite their occurrence in the head and neck region, this is a very rare finding in the oral cavity and one among 4-7 % of patients reported to be affected by neurofibromatosis displaying oral manifestations. Plexiform neurofibroma is said to be indicative of Von Recklinghausen’s disease (VRD) even though it may be the only manifestation of the disease 2 . Ideally surgical resection should be the treatment of choice and the diagnosis has to be confirmed by both histological and immunohistochemistry examination with S-100 tumour marker. Affected patients need thorough clinical examination and regular follow up to detect any recurrence, any malignant degeneration, or any manifestations of Von Recklinghausen’s disease.
Authors and Affiliations
Dr R. Keerthi
Keywords
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