A RETROSPECTIVE DESCRIPTIVE STUDY OF ALUMINIUM PHOSPHIDE POISONING IN A TERTIARY CARE CENTRE OF CENTRAL INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 21
Abstract
BACKGROUND Poisonings due to metal phosphides in general and Aluminium phosphide (ALP) in particular are a global public health problem. Aluminium phosphide is an inorganic phosphide that has been in use since 1940 as an insecticide and rodenticide for domestic grain preservation and in grain processing facilities. After coming in contact with water, moisture or hydrochloric acid in the stomach, ALP liberates highly toxic phosphine gas (PH3) which produces widespread organ toxicity primarily involving the lungs, heart, liver and kidneys. In India, Aluminium phosphide is widely available as there is no restriction on its sale, that is why it is a common suicidal poison. The past four decades have witnessed high rates of mortality (37% to 100% in various studies) with ALP poisoning. Aims and Objectives- To study the clinical profile and treatment outcomes of ALP poisoning in a tertiary care centre of central India. MATERIALS AND METHODS This is a retrospective descriptive study of patients of Aluminium phosphide poisonings, in which their clinical profile and outcome of management was studied. The five-year study period was from Jan 2009 to Dec 2013. RESULTS Aluminium phosphide is a commonly used insecticide for suicidal poisonings. Aluminium phosphide is easily available, as it is a commonly used insecticide and rodenticide in wheat producing areas of central India. A total of 68 patients of aluminium phosphide poisoning were studied in the study period of five years. Ninety four percent patients between the age group of 15 - 30 years represented young age group. The intent of poisoning in all the cases was suicidal. There was no correlation between mortality and age or sex. CONCLUSION Aluminium phosphide poisoning is a common lethal insecticide poisoning. Easy availability and lack of control on its sales makes it a common suicidal poison. As an effective antidote is still not available, the treatment mainly remains supportive only. Stricter governmental control on its distribution and sale can help in reducing the mortality due to Aluminium phosphide poisonings. Larger controlled trials are required for comparative evaluation of various methods of management and to assess their outcome.
Authors and Affiliations
Aneeta Datey, Ashima Datey Chakrabarty, Abhishek Agarwal
Keywords
Related Articles
- EP ID EP431655
- DOI 10.14260/jemds/2018/582
- Views 62
- Downloads 0
MULTIPLE PRIMARY MALIGNANT NEOPLASMS- AN INTERESTING CASE REPORT
PRESENTATION OF CASE A 65-year-old male with complaints of lump in left breast since 2 years. CT scan findings were non-homogeneous mass in left breast along with bilateral axillary lymphadenopathy. Lumpectomy was perfor...
SEROPREVALENCE OF HEPATITIS C VIRUS AMONG BLOOD DONORS IN A TERTIARY CARE CENTRE IN KERALA
BACKGROUND Transfusion transmitted infections continue to be a threat to safe blood transfusion practices. The problems of window period is an important aspect in the detection of viral infections. Most persons infected...
MANAGEMENT OF INTRA-ARTICULAR CALCANEAL FRACTURES WITH REDUCTION AND PERCUTANEOUS FIXATION
BACKGROUND Calcaneum, the largest and strongest cancellous tarsal bone is very well designed to bear the body weight. It endures a lot of daily activity stresses. The bone is unique in that it is actually hard on the out...
ABDOMINAL FLAPS IN THE MANAGEMENT OF UPPER LIMB DEFECT- OUR EXPERIENCE
BACKGROUND Soft tissue defects in upper limb are commonly seen as a sequel to trauma and burns, leading to exposure of important structures such as vessels, nerves, tendons and bone. These structures require primary cove...
A COMPARATIVE STUDY OF KETAMINE (HEAVY) WITH 5% LIGNOCAINE (HEAVY) INTRATHECALLY FOR CAESAREAN SECTION- A RANDOMISED CONTROL TRIAL
BACKGROUND Spinal anaesthesia for caesarean section has gained popularity since it decreases the complications of general anaesthesia. High incidence of spinal hypotension, neonatal bradycardia and decreases in neurobeha...