A COMPARATIVE STUDY OF KETAMINE (HEAVY) WITH 5% LIGNOCAINE (HEAVY) INTRATHECALLY FOR CAESAREAN SECTION- A RANDOMISED CONTROL TRIAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 49
Abstract
BACKGROUND Spinal anaesthesia for caesarean section has gained popularity since it decreases the complications of general anaesthesia. High incidence of spinal hypotension, neonatal bradycardia and decreases in neurobehavioral scores are not uncommon with the use of 5% Lignocaine. The aim is to evaluate the efficiency and safety of Ketamine as a sole anaesthetic agent and compare it with 5% Lignocaine in spinal anaesthesia. MATERIALS AND METHODS This randomised control trial is conducted among 100 pregnant females belonging to ASA I and I-E in the age 25-35 years, weighing 41-75 kg and height of 140-165 cm. Group 1 (n=50) patients received 50 mg of 5% lignocaine intrathecally. Group 2 (n=50) patients received 75 mg of Preservative-free ketamine HCL in 25% Dextrose intrathecally. Onset of sensory blockade, maximum spread & duration of analgesia, onset & duration of motor blockade, APGAR score at 1 & 5 min. are compared. Intraoperative hypotension, bradycardia and other side effects are noted. RESULTS Onset of sensory block in group 1 is faster than group 2 (p <0.001). Maximum spread and duration of analgesia was statistically insignificant between two groups. Onset of motor block in group 1 is faster than group 2 (p <0.05). Duration of motor block and APGAR at 1& 5 min. was statistically significant between two groups. Intraoperative hypotension is more common in group 1 than group 2. CONCLUSION Intrathecal ketamine provides good analgesia, duration of analgesia and motor blockade obtained is good and adequate for caesarean section. So ketamine is a safe and effective anaesthetic agent and it can be tried safely in emergency caesarean section.
Authors and Affiliations
Loganathan S, Karthick Raj A
Keywords
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- EP ID EP219112
- DOI 10.14260/Jemds/2017/813
- Views 62
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