A Retrospective Study of Fungal Corneal Ulcers in the South Sharqiyah Region in Oman

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A Retrospective Study of Fungal Corneal Ulcers in the South Sharqiyah Region in Oman

Journal Title: Sultan Qaboos University Medical Journal - Year 2009, Vol 9, Issue 1

Abstract

To study the incidence, identify the risk factors and determine the predominant microorganisms and treatment regimen of fungal corneal ulcers. Methods: Tis was a retrospective analysis of corneal ulcers treated in the Ophthalmology Department of Sur Hospital, Oman, undertaken from January 2004 to December 2007. Medical and microbiology records of thirty two culture proven cases of fungal keratitis were reviewed for risk factors, laboratory findings and response to treatment. Results: Out of the total 242 corneal ulcers, ï›œ3.22 % were fungal. Among the ï›œ02 culture positive cases, 3ï›œ.38 % were fungal isolates. Fusarium spp (50%) and Aspergillus spp (34.4%) predominated in the hyaline fungal spectrum. Te important risk factors were topical steroid usage in 3ï›œ.25 % of cases and ocular injury in 25 %. Te majority of cases (90.62%) responded to 2% ketoconazole alone or in combination with 0.ï›œ5% amphotericin B. Conclusion: Fungal ulcer remains one of the leading causes of visual disability. Indiscriminate use of topical steroids and ocular trauma are the most important risk factors. Filamentous fungi are common aetiological agents in this region. Topical ketoconazole and amphotericin B were very effective for most of the cases.

Authors and Affiliations

Tara Idiculla| Department of Ophthalmology, Sur Regional Hospital, Sultanate of Oman, George Zachariah| Department of Ophthalmology, Sur Regional Hospital, Sultanate of Oman, BR Keshav| Department of Ophthalmology, Sur Regional Hospital, Sultanate of Oman, Somansu Basu| Department of Ophthalmology, Sur Regional Hospital, Sultanate of Oman

Keywords

Corneal ulcer Keratitis Fungi Culture media

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