A RETROSPECTIVE STUDY OF THE IMPACT OF RADIATION FRACTIONATION ON PAINFUL BONE METASTASIS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 13
Abstract
BACKGROUND Bone metastasis and bone pain are most detrimental to the life of cancer patients. There is a significant discrepancy between the physician estimate of pain and the pain level reported by the patient. We wanted to evaluate the effectiveness of radiotherapy in reducing the bone pain and identify the suitable dose fractionation schedule. METHODS This is a retrospective cohort study analysis carried out in patients with bone metastasis who presented to radiotherapy department, MCH Kottayam from August 2010 to January 2015 and were treated with radiotherapy. Data collected from the case records to assess the response to radiotherapy in patients who were treated with either 20GY/5# or 8GY/1#, response was assessed periodically with the universal pain assessment tool. RESULTS Even though there was difference in the type of pain controlled by the two radiation fractions, the overall pain score showed no statistically significant difference in the overall pain control between the two arms. CONCLUSIONS 20 Gy/5 fractions and 8 Gy/single fraction schedules of radiotherapy were found to be similar in terms of rates of pain relief, narcotic use, and pathologic fracture. In terms of acute control of patient symptoms of bone pain, either of the two schedules may be used without compromising outcome.
Authors and Affiliations
Suresh Kumar K, Flowerlit Thomas, Ajith Nair, Mintu Mathew, Snigdha P. P
Keywords
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- EP ID EP555728
- DOI 10.14260/jemds/2019/222
- Views 77
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