HISTOMORPHOLOGICAL STUDY OF PAEDIATRIC LIVER TUMOURS-A SINGLE INSTITUTION EXPERIENCE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 22
Abstract
[b] INTRODUCTION[/b]: Liver tumours are uncommon in infancy and childhood, accounting to 1-2% of all paediatric neoplasms. Though rare, 2/3rds of cases unfold as malignancies. These neoplasms differ considerably from their counterparts in the older age group. The present study reflects the Niloufer experience, a well established tertiary referral centre, Hyderabad. [b]AIMS & OBJECTIVES[/b]: To analyze the various paediatric liver tumours ,to review the frequency and histopathology of paediatric liver tumours and to review the existing literature on liver tumours of infancy and childhood. [b]METHODS AND MATERIALS[/b]: A retrospective analysis of children aged between 8 days and 11 years diagnosed with hepatic tumours was done over a period of 7 years (July 2004 –June 2011).The cases were analyzed based on clinical, radiological, biochemical, gross and microscopic findings. [b]RESULTS[/b]: Of the 22 cases studied, 16 were malignant tumours of which 11 cases were diagnosed as hepatoblastoma and of the remaining 6 cases, 4 were diagnosed as infantile hemangioendothelioma, 2 as mesenchymal hamartomas. The incidence in males is slightly higher than in females reflected by the ratio of 1.6:1.[b]CONCLUSIONS[/b]: The spectrum of liver tumours in paediatric population is different from that of the older age group. From the present study, we can gather that hepatoblastoma by far is the most common childhood hepatic malignancy unlike hepatocellular carcinoma in the adults. This study also throws light on the incidence in different paediatric age group, difference in male to female incidence, clinical presentation and biochemical data
Authors and Affiliations
Ramani M, Geetha K, Radhika Krishna, Ramesh Reddy, Srinivas Reddy, Challa Madhuri, Sowjanya R
Keywords
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- EP ID EP132994
- DOI 10.14260/jemds/782
- Views 82
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