A REVIEW ARTICLE TO DEVELOP SUSTAIN RELEASE RIVAROXABAN FORMULATION
Journal Title: Journal of Atoms and Molecules - Year 2012, Vol 2, Issue 2
Abstract
Rivaroxaban is an oral anticoagulant invented and manufactured by Bayer; in a number of countries it is marketed as Xarelto.[1] In the United States, it is marketed by Janssen Pharmaceutical.[2] It is the first available orally active direct factor Xa inhibitor. Rivaroxaban is well absorbed from the gut and maximum inhibition of factor Xa occurs four hours after a dose. The effects last 8–12 hours, but factor Xa activity does not return to normal within 24 hours so once-daily dosing is possible.
Authors and Affiliations
K. Sapna, G. Sudhakar, Dr. R. Santosh Kumar
Keywords
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