A review: Gastroretentive drug delivery system (grdds)
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2015, Vol 3, Issue 1
Abstract
One novel approach in this area is GRDDSs (Gastro Retentive Drug Delivery System). GRDDSs can improve the controlled delivery of drugs that have an absorption window by continuously releasing the drug for a prolonged period of time before it reaches its absorption site.The purpose of writing this review was to investigate, compile and present the recent as well as past literatures in more concise way with special focus on approaches which are currently utilized in the prolongation of gastric residence time. These includes floating system, swelling and expanding system, bio/mucoadhesive system, high density system and other delayed gastric emptying devices. The present review addresses briefly about the classification, formulation consideration for GRDDS, factors controlling gastric retention, merits, demerits and applications of gastroretentive drug delivery systems.
Authors and Affiliations
Meenakshi Jassal| Himachal Institute of Pharmacy, Paonta sahib, HP, India, Ujjwal Nautiyal| Himachal Institute of Pharmacy, Paonta sahib, HP, India, Jyotsana Kundlas| Himachal Institute of Pharmacy, Paonta sahib, HP, India, Devendra singh| Tirupati life science, Paonta Sahib, HP, India
Keywords
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