A Review of Animal Laboratory Practice in the COVID-19 and Safety Concerns
Journal Title: Translational Research in Urology - Year 2020, Vol 2, Issue 1
Abstract
The research in biomedical sciences is based on basic research on animals. As a consequence of the coronavirus disease-2019 (COVID-19) pandemic, many research projects involving animal studies have faced interruptions due to the raised concerns about the safety of working with animals The disruption in such research projects has raised significant concerns in biomedical scientific research worldwide. It seems necessary to assess and evaluate the safety and feasibility of conducting research projects on animal models. This study provides evidence on the feasibility of continuing the research activities in animal laboratories during the COVID-19 pandemic. According to the results of studies, the risk of COVID-19 is low in routine laboratory animals, including mice, rats, and pigs. By examining the available data from our animal laboratory, continuing research activities on low-risk animals, with adequate safety and personal protection equipment being available at the facility, animal studies could be carried forward without endangering the safety of the researcher and the society.
Authors and Affiliations
Rahil Mashhadi; Fatemeh Khatami; Leyla Zareian Baghdadabad; Alireza Namazi Shabestari; Fateme Guitynavard; Leonardo Oliveira Reis
Keywords
Related Articles
- EP ID EP704190
- DOI 10.22034/TRU.2020.249149.1033
- Views 68
- Downloads 0
The Promising Role of MicroRNAs, Long Non-Coding RNAs and Circular RNAs in Urological Malignancies
Nowadays, non-communicable diseases are the leading cause of death worldwide. Cancer management has been a significant challenge for public health in the last decade. Aging of the population and Urbanization has induced...
Unusual Emphysematous Chest Wall with Progressive Loculated Empyema and Abscess Formation Post Emphysematous Pyelonephritis: A Case Report
Introduction The abdominal emphysematous pyelonephritis and its association with lung involvement in diabetic patients can be life treating and should be the cure as soon as possible. Case presentation Our case is a 3...
The Impact of Potassium Citrate on the Kidney Stones Treatment in Rat
Introduction: Nephrolithiasis is one of the most common prevalent diseases in the human population, with a high recurrence rate. Although the prophylaxis effect of potassium citrate in renal calculi is well known, its th...
An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells
Intravesical Bacillus Calmette-Guerin (BCG) is approved for non-muscle invasive bladder cancer treatment a long time ago. Chimeric antigen receptor T cells (CAR-Tcell), are T cells are genetically engineered T cells that...
Phosphatase and Tensin Gene Associated with Features of Aggressive Prostate Cancer
Introduction The current study examined the clinical impacts of phosphatase and tensin (PTEN) expression in prostate cancer (PCa) using immunohistochemistry. Methods 50 patients with a mean age of 66.4±7.3 years who h...