A Review of Association betweenEarly Exposure to Infant-feeding formulas and Type 1 Diabetes among Children
Journal Title: International Journal of Biomedical and Advance Research - Year 2017, Vol 8, Issue 5
Abstract
The increasing incidenceof type 1 diabetes among children calls for a thorough understanding of the disease to stem its growth. Early exposure to infant-feeding formulas has been linked with the disease and several mechanisms of action have been proposed. However, it is unclear the exact mechanism by which infant-formulas aid in the pathogenesis of type 1 diabetes. This paper reviewed and articulated several hypotheses proposed as the mechanisms of action of infant formulas in the onset of type 1 diabetes. The Google search engine was used to search for relevant information on the internet from reputable sources such as PubMed, Google Scholar, among others.The majority of the studies reviewed overwhelmingly agreed early exposure to infant-feeding formulas may contribute to the pathogenesis of type 1 diabetes among children. Cow milk, for example, contains bovine insulin, which differs from human insulin with 3 amino acids, and can cause immune reactions in children. Gluten-containing diets such as wheat may cause proportional changes in immune cell populations or modify the cytokine/chemokine pattern towards an inflammatory profile. Concentrated soy-based formulas contain active estrogenic endocrine disruptors. Fruits, berries and roots may be infected with toxic antibiotics, which can start off autoimmunity. Nursing moms are therefore advised to breastfeedtheir babies for a long time before introducing infant-feeding formulas, especially those with a family with a history of diabetes.
Authors and Affiliations
Yahaya T, Oladele, EO, Umar, J
Keywords
Related Articles
- EP ID EP383810
- DOI 10.7439/ijbar.v8i5.4047
- Views 83
- Downloads 0
Role of oral medicine specialist in palliative care
Oral cancer, the sixth most common malignancy, is a major cause of cancer morbidity and mortality worldwide. The leading etiological factor behind this is consumption of tobacco by Indian population. Palliative care is a...
Association between thyroid hormone disorders and renal dysfunction
Background: Thyroid hormones perform a wide range of metabolic functions. Relationship between thyroid diseases and kidney function initially described were clinically subtle. It has been suggested that patients of thyro...
Comparison of clinical performance of I-Gel with LMA-Proseal in elective surgeries under general anesthesia
Aim: To compare insertion characteristics of two different supraglottic devices [I-gel and LMA-Proseal] and to observe any associated complications. Materials and Methods: This prospective, randomized study was conducted...
A Review of Association betweenEarly Exposure to Infant-feeding formulas and Type 1 Diabetes among Children
The increasing incidenceof type 1 diabetes among children calls for a thorough understanding of the disease to stem its growth. Early exposure to infant-feeding formulas has been linked with the disease and several mecha...
EFFECT OF GARLIC ON TOTAL ANTIOXIDANTS IN ALLOXAN INDUCED DIABETES MELLITUS RATS
Background and Objective: Diabetes mellitus is the single most common disorder across the globe. Although the metabolism of carbohydrates in diabetes is well characterized, the role of total antioxidants in diabete...