A REVIEW ON CONTROLLED RELEASE BUCCOADHESIVE BILAYERED TABLET OF PROCHLORPERAZINE MALEATE
Journal Title: International Journal of Pharmaceutical and Biological Science Archive - Year 2018, Vol 6, Issue 1
Abstract
The oral mucosa can be divided into two general regions, the outer vestibule and the oral cavity. The vestibule is bounded on the outside by the lips and cheeks and on the inside by the upper and lower dental arches. Since sublingual administration of drugs interferes with eating, drinking and talking, this route is generally considered unsuitable for prolonged administration. The term bioadhesion refers to any bond formed between two biological surfaces or a bond between a biological and a synthetic surface. Although the target of many bioadhesive delivery systems may be a soft tissue cell layer (i.e. epithelial cells), the actual adhesive bond may form with either the cell layer, a mucous layer or a combination of the two. The mucoadhesive power of a polymer is affected by the nature of polymer and also by the nature of surrounding medium. KEY WORDS: Tablet, bioadhesion,mucoadhesive, prochlorperazine maleate
Authors and Affiliations
Lalit Jogsingh Rajpurohit
Keywords
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