A Review on Fast Dissolving Tablet Technology.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2013, Vol 2, Issue 1
Abstract
Fast dissolving Tablets are disintegrating and/or dissolve rapidly in the saliva without the need for water. Some tablets are designed to dissolve in saliva remarkably fast, within a few seconds, and are true fast-dissolving tablets. Others contain agents to enhance the rate of tablet disintegration in the oral cavity, and are more appropriately termed fast-disintegrating tablets, as they may take up to a minute to completely disintegrate. Oral delivery is currently the gold standard in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. This tablet format is designed to allow administration of an oral solid dose form in the absence of water or fluid intake. Such tablets readily dissolve or disintegrate in the saliva generally within <60 seconds. Fast- or mouth dissolving tablets have been formulated for pediatric, geriatric, and bedridden patients and for active patients who are busy and traveling and may not have access to water. Such formulations provide an opportunity for product line extension in the Many elderly persons will have difficulties in taking conventional oral dosage forms (viz., solutions, suspensions, tablets, and capsules) because of hand tremors and dysphagia. Swallowing problems also are common in young individuals because of their underdeveloped muscular and nervous systems. Other groups that may experience problems using conventional oral dosage forms include the mentally ill, the developmentally disabled, and patients who are uncooperative, on reduced liquid-intake plans, or are nauseated. In some cases such as motion sickness, sudden episodes of allergic attack or coughing, and an unavailability of water, swallowing conventional tablets may be difficult.
Authors and Affiliations
Lalji Amipara*| Jaipur college of pharmacy, Jaipur(Rajasthan), India., M. M. Gupta| Jaipur college of pharmacy, Jaipur(Rajasthan), India.
Keywords
Related Articles
- EP ID EP1594
- DOI -
- Views 398
- Downloads 24
A STUDY OF ANTI-HYPERLIPIDEMIC ACTIVITY OF MARKETED FORMULATIONS OF TERMINALIA ARJUNA POWDER USING EXPERIMENTAL ANIMAL MODEL
Hyperlipidemia is a disorder of lipid metabolism which is major risk of coronary heart disease. Now a day’s synthetic drugs have been associated with number of side effects but herbal medicines have lipid lowering and an...
AN EMPIRICAL STUDY ON THE PREVALENCE OF CHILDREN WITH DISABILITY IN MANGALORE
Children with disability are an important social concern in the community. This study aims to report the different types of disability among school going children in Mangalore. Data were collected from the Inclusive Edu...
MOLECULAR DETECTION OF HELICOBACTER PYLORI AMONG GASTRODUODENITIS AND PEPTIC ULCER PATIENTS IN KHARTOUM STATE
Background: Helicobacter pylori infection is associated with gastroduodenitis , gastric ulcer and duodenal ulcer . Many of studies have released causes of gastric ulcer and duodenal ulcer (approximately 95% of duodenal u...
BIOLOGICALLY ACTIVE SECONDARY METABOLITES FROM KALANCHOE TOMENTOSA
Phytochemical study of the ethanolic extract of Kalanchoe tomentosa (Crassulaceae) resulted in the isolation of 14 compounds identified as; α-amyrin acetate (1), friedelin (2), glutinol (3), 1-dotriacontanol (4), phytol...
EXPLORATION OF MUCIN PROTEIN FROM MACROCHLYMUS INDICA AND DETERMINED ITS IMMUNOGENICITY STUDIES
Introduction – Mucins are included under the category of high molecular weight (i.e. O-glycosylated) proteins which plays a crucial role with respect to protection, lubrication and acid resistance of the epithelial cell...