A Review on Fast Dissolving Tablet Technology.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2013, Vol 2, Issue 1
Abstract
Fast dissolving Tablets are disintegrating and/or dissolve rapidly in the saliva without the need for water. Some tablets are designed to dissolve in saliva remarkably fast, within a few seconds, and are true fast-dissolving tablets. Others contain agents to enhance the rate of tablet disintegration in the oral cavity, and are more appropriately termed fast-disintegrating tablets, as they may take up to a minute to completely disintegrate. Oral delivery is currently the gold standard in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. This tablet format is designed to allow administration of an oral solid dose form in the absence of water or fluid intake. Such tablets readily dissolve or disintegrate in the saliva generally within <60 seconds. Fast- or mouth dissolving tablets have been formulated for pediatric, geriatric, and bedridden patients and for active patients who are busy and traveling and may not have access to water. Such formulations provide an opportunity for product line extension in the Many elderly persons will have difficulties in taking conventional oral dosage forms (viz., solutions, suspensions, tablets, and capsules) because of hand tremors and dysphagia. Swallowing problems also are common in young individuals because of their underdeveloped muscular and nervous systems. Other groups that may experience problems using conventional oral dosage forms include the mentally ill, the developmentally disabled, and patients who are uncooperative, on reduced liquid-intake plans, or are nauseated. In some cases such as motion sickness, sudden episodes of allergic attack or coughing, and an unavailability of water, swallowing conventional tablets may be difficult.
Authors and Affiliations
Lalji Amipara*| Jaipur college of pharmacy, Jaipur(Rajasthan), India., M. M. Gupta| Jaipur college of pharmacy, Jaipur(Rajasthan), India.
Keywords
Related Articles
- EP ID EP1594
- DOI -
- Views 456
- Downloads 24
A Review on Nanocochleate – A Novel Lipid Based Drug Delivery System.
Nanaocochleate represent a new approach for oral and systemic delivery of drugs . It is a novel lipid-based system which is suitable for the oral and systemic administration of a wide variety of molecules with important...
BRINE SHRIMP LETHALITY TEST AND ANTI-PROLIFERATION TEST AGAINST HUMAN CANCER-ORIGIN CELL LINES USING ETHANOLIC AND WATER EXTRACTS OF SELAGINELLADOEDERLEINII HIERON
Most of the properties of herbal products claimed in traditional use are based on traditional knowhow and/or empirical observations. Support from scientific evaluation and validation is thus crucial. Selaginella doederle...
DEVELOPMENT AND VALIDATION OF ANALYTICAL METHODS OF INDOMETHACIN IN RABBIT BLOOD PLASMA BY RP-HPLC TECHNIQUE
The objective of the present work involved the development of simple, rapid, sensitive and cost effective RP-HPLC method for the estimation and quantification of indomethacin in rabbit plasma to evaluate their linearity...
OCCURRENCE OF VARIOUS SOFT TISSUE TUMORS IN NORTH KARNATAKA
Soft tissue can be defined as nonepithelial extra skeletal tissue of the body; benign soft tissue tumors outnumber malignant tumors by a margin of about 100:1 in a hospital population. The diagnosis and management of sof...
HUMAN GENOME DESIGN, RESHUFFLES AND GENOMIC DISORDERS.
Many human hereditary disorders come about because of unstable chromosome anomalies, where there is an addition or loss of hereditary material. Such irregular characteristics regularly disturb extensive amounts of dosage...