A Review on Nanocochleate – A Novel Lipid Based Drug Delivery System.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2013, Vol 2, Issue 1
Abstract
Nanaocochleate represent a new approach for oral and systemic delivery of drugs . It is a novel lipid-based system which is suitable for the oral and systemic administration of a wide variety of molecules with important therapeutic activities, including drugs, genes, and vaccine antigens. This novel formulation approach is applicable to macromolecules as well as small molecule drugs that are hydrophobic and that possess poor oral bioavailability. Studies for oral delivery of clinically important drugs are being carried out in suitable animal models to evaluate their efficacy.
Authors and Affiliations
Swapnil E. Yeole*| P. E. Society’s Modern College of Pharmacy, Nigdi, Pune-411 044 (Maharashtra), Smita S. Pimple| P. E. Society’s Modern College of Pharmacy, Nigdi, Pune-411 044 (Maharashtra), Pravin D. Chaudhari| P. E. Society’s Modern College of Pharmacy, Nigdi, Pune-411 044 (Maharashtra)
ROLE OF BHALLATAKARASAYANA IN CANCER
An integrated approach is required in the management of cancer by using the knowledge gained through various scientific developments. Thousands of traditional compounds are being screened worldwide to validate their effi...
Seroprevalence of Herpes Simplex Virus (HSV-1 and HSV-2) Infections in Sudanese Renal Transplant Recipients
Introduction: Viruses are among the most common causes of opportunistic infections after transplantation, because of their immunosupressed condition. Aim: This study aimed to determine Herpes Simplex Virus-1 and Herpes...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF LEVOSULPIRIDE AND PANTOPRAZOLE IN TABLETS BY RP-HPLC METHOD
A simple, precise, accurate, rapid and economical reverse phase high-pressure liquid chromatographic method has been developed as per ICH norms for the simultaneous estimation of Levosulpride and pantoprazole sodium from...
FORMULATION & CHARACTERIZATION OF TOPICAL GEL CONTAINING SANDALWOOD OIL OF NAPROXEN FOR THE TREATMENT OF RHEUMATOID ARTHRITIS
The present research study is based on development of a topical gel formulation of naproxen containing sandalwood oil. The oral administration of naproxen comes with potential gastrointestinal disorders which can be avoi...
ANTIOXIDANT AND ANTIDIABETIC ROLE OF PETROSELINUM CRISPUM AGAINST STZ-INDUCED DIABETES IN RATS
Petroselinum crispum (Parsley) has been reported to have a number of possible medicinal attributes. The aim of this work is to evaluate the ameliorative effect of parsley aqueous extract (PAE) against STZ-induced diabeti...