Seroprevalence of Herpes Simplex Virus (HSV-1 and HSV-2) Infections in Sudanese Renal Transplant Recipients
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2013, Vol 2, Issue 5
Abstract
Introduction: Viruses are among the most common causes of opportunistic infections after transplantation, because of their immunosupressed condition. Aim: This study aimed to determine Herpes Simplex Virus-1 and Herpes Simplex Virus-2 (HSV-1 and 2) seropositivity among Sudanese kidney transplant recipients. Material and Methods: One hundred eighty four serum samples of 92 Sudanese Kidney transplant recipients and 92 control group (blood donors) were tested serologically to detect HSV-1 and HSV-2 IgG and IgM antibodies using an enzyme-linked immunosorbent assay. Results: The HSV1/2 IgG was positive in 99% of the renal transplant recipients, while HSV1/2 IgM was positive in 50% of renal transplant recipients. In control group, HSV1/2 IgG was positive in 90% while HSV1/2 IgM was positive in 6%. For HSV1/2 IgG and HSV1/2 IgM Seroprevalence was higher in females (100%, 53%) compared with males (94%, 25%). There was association between HSV seropositivity and age (P<0.001). Conclusions: The Seroprevalence of HSV-1 and HSV-2 among study kidney transplant recipients was high (99%, 50% for HSV 1-2 IgG and IgM antibody respectively), so this viral infection must be remains in concern.
Authors and Affiliations
Shaza Abd Allah M. Ahmed*| AL-Neelain University, Faculty of Medical laboratory Science; Department of Microbiology., Mustafa E M Yassin| AL-Neelain University, Faculty of Medical laboratory Science; Department of Microbiology., Khalid A. Enan| AL-Neelain University, Faculty of Medical laboratory Science; Department of Microbiology., Khalid Abdalmoniem| AL-Neelain University, Faculty of Medical laboratory Science; Department of Microbiology., Mohammed Nafi and Isam M Elkhidir| AL-Neelain University, Faculty of Medical laboratory Science; Department of Microbiology.
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