A REVIEW ON SOLID LIPID NANOPARTICLES; FOCUS ON EXCIPIENTS AND FORMULATION TECHNIQUES
Journal Title: International Journal of Pharmaceutical Sciences and Research (IJPSR) - Year 2019, Vol 10, Issue 9
Abstract
Nanotechnology has brought about a significant change in the drug delivery system. A plethora of BCS class II drugs are formulated as solid lipid nanoparticles (SLN) due to its poor solubility and bioavailability and has potential applications in drug delivery system. The formulation of SLN involves use of a different type of surfactants and lipids in different concentrations which has shown a greater impact on various physicochemical parameters such as entrapment efficiency, drug release, particle size, zeta potential, storage and stability of the drug. Apart from its unique size-dependent property, merits and demerits, different excipients characterization technique, scale up, storage and stability are reviewed.
Authors and Affiliations
P. K. Lakshmi et al.
FORMULATION AND IN-VITRO EVALUATION OF FAST DISSOLVING TABLETS OF LACOSAMIDE USING NATURAL SUPER DISINTEGRANTS
Fast dissolving tablets are those which disintegrates rapidly within the mouth and taken without consumption of water. The present work is concerned with the formulation and in-vitro evaluation of Lacosamide fast dissolv...
SYNTHESIS AND ANTIMICROBIAL STUDIES OF NOVEL GLYCOSYL THIOCARBAMIDES
Glycosyl isothiocyanates have been widely used as important intermediates in the synthesis of many biologically active glycosyl derivatives. The glycosyl isothiocyanates have been the focus of synthetic attention during...
Evaluation of Antidiabetic Activity of Triumfetta Pilosa Roth in Streptozotocin-Induced Diabetic Rats
The present study aims to evaluate medicinal use of Triumfetta pilosa for the treatment of diabetes. Antidiabetic activity of ethanolic extract of Triumfetta Pilosa Roth was evaluated for in-vivo hypoglycemic activity u...
DRUG UTILIZATION PATTERN IN GERIATRIC PATIENTS OF GENERAL MEDICINE IN A SECONDARY CARE HOSPITAL
The purpose of the research was to assess the prescribing pattern in geriatrics and to analyze the prescription using World Health Organization (WHO) core prescribing indicators and American Geriatric Society (AGS) Beers...
SYNTHESIS AND CYTOTOXICITY STUDY OF PLANT DERIVED NANOCOMPOSITE
The present study is a small attempt of synthesis of gold nanocomposites with anticancer drug cisplatin and their cytotoxicity test on HeLa cell line. There are many well-established reports on the synthesis of gold nano...