A REVIEW ON THE THERAPEUTIC POTENTIAL OF QUINOXALINE DERIVATIVES
Journal Title: World Journal of Pharmaceutical Research - Year 2017, Vol 6, Issue 12
Abstract
Quinoxaline nucleus based derivatives have attracted researcher’s attention due to privileged and extensive applications in medicine, pharmaceuticals and pharmacological fields. Quinoxaline moiety is a part of various antibiotics such as echinomycine, levomycine, actinoleutine and also act as antiviral, anti-diabetic, anti-inflammatory, kinase inhibitors, anticancer, ion channel regulators and anti-protozoa agent. Various synthetic methodologies and strategies are developed to prepare quinoxaline compound libraries due to pivotal focal point of research activity in the field of pharmacology and medicine. In this review the substituted quinoxaline scaffolds synthetic chemistry, biological activities and applications are summarized.
Authors and Affiliations
Ali Irfan
Keywords
Related Articles
- EP ID EP618381
- DOI -
- Views 138
- Downloads 0
METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF SAROGLITAZAR IN PHARMACEUTICAL DOSAGE FORM BY RP-HPLC
A simple, sensitive and rapid reverse phase high performance liquid chromatographic method was developed for the estimation of Saroglitazar in tablet dosage form. A C18 Inertsil ODS column (250 × 4.6 mm, 5μm particle siz...
ASSESSMENT OF KNOWLEDGE ABOUT BREAST SELF – EXAMINATION AMONG ADULT YOUNG FEMALES
Screening for early detection of diseases is an important public health principle. Breast Self Examination (BSE) is a process whereby women examine their breasts regularly to detect any abnormal changes to seek prompt me...
ROLE OF AKSHI TARPANA IN THE MANAGEMENT OF EYE DISEASES
Eyes hold special status among all the sense organs because good vision is crucial for social and intellectual development of human beings. Hence authentic classics prescribed several preventive measures and systemic, su...
ORAL GLUCOSE TOLERANCE TEST (OGTT) WITH WHOLE PLANTS OF ALOCASIA FORNICATA ROXB. (ARACEAE)
Background: Alocasia fornicata is an Araceae family plant of which not much is known about its pharmacological properties. As such, the objective of this study was to evaluate the antihyperglycemic potential of methanoli...
CLINICAL DIAGNOSTIC APPROACH OF BACTERIAL INFECTIONS: A REVIEW
The prevalence of bacterial infections is increasing day by day. Most common bacterial infections are tuberculosis, meningitis, respiratory tract infections, gastro enteritis, endocarditis, urinary tract infections, typh...