A REVIEW ON THIRD GENERATION CEPHALOSPORINS
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2017, Vol 4, Issue 8
Abstract
Rational use of drugs refers as patients receive medicines according to their clinical needs at lowest cost. The beta lactam antibiotics alter cell wall biosynthesis. Cephalosporins belong to beta lactam antibiotics and classified into 1st, 2nd, 3rd, and 4th generation. If huge number of organisms are involved in diseases then generation wise cephalosporins are used. The beta lactam antibiotics are commonly used to cure after operation wounds due to its extended spectrum of activity and clinical effectiveness and high safety profile. The third- generation cephalosporins are widely used antibiotics in both males and females for treatment of different diseases and have lesser side effects as compared to aminoglycosides and polymixins. For Enterobacter aerogenes the magnitude of susceptibality to third generation cephalosproins is higher than amikacin. Ceftriaxone is widely used third generation cephalosporins. Cefotaxime shows the effectiveness in uncomplicated urinary tract infection. Patients who are allergic to penicillins have more chances of adverse drug reactions to cephalosporins. Third generation cephalosporins show extensive resistance due to overutilization and improper utilization. The danger of third generation cephalosporins resistance was especially high in nosocomially-produced scenes of unconstrained bacterial peritonitis. There should be consistent surveillance, investigation and efforts to deal with resistance related problems.
Authors and Affiliations
Asma Riaz
Keywords
Related Articles
- EP ID EP630677
- DOI -
- Views 147
- Downloads 0
INSULIN PROFILING AND HISTO-PANCREATIC ARCHITECTURE IN STZ–INDUCED DIABETES MELLITUS RATS’ MODEL TREATED WITH MISTLETOE AND DRUM-STICK AQUEOUS LEAF EXTRACTS
Reports showed that antioxidants protect against disabling effects of Diabetes mellitus by mopping up free oxygen and superoxide radicals. The study is therefore aimed at investigating some ameliorative effects of Mistle...
MAGIC MUSHROOM A POTENT HALLUCINOGEN: A CRITICAL REVIEW
Hallucinogen, the substance which can alter a person's perception of reality. Some naturally occurring substances proved their potential to act as a hallucinogen. Amongst, Psilocybin (4-phosphorylox-N, N-dimethyltryptami...
ASSESSMENT OF SOME BIOCHEMICAL PARAMETERS AMONG SMOKERS
This study was designed to evaluate the serum levels of creatinine, urea and activities of Alkaline phosphatase (ALP), Gamma glutamyl transferase (GGT), Creatine kinase (CK) and Lactate dehydydrogenase (LDH) among cigare...
ZIKA VIRUS OUTBREAK: THE GLOBAL ENDEMIC TO PANDEMIC
Zika virus is a member of the Flaviviridae family and is transmitted to humans by mosquitoes. It is related to other pathogenic vector borne flaviviruses including dengue, West-Nile and Japanese encephalitis viruses but...
A CROSS SECTIONAL STUDY OF KNOWLEDGE, ATTITUDE AND PRACTICES OF MENSTRUAL HYGIENE AMONGAU FEMALE STUDENTS
Menstruation and menstrual practices are associated with taboos and socio-cultural restrictions. Good hygienic practices such as the use of sanitary pads and adequate washing of genital area are essential during menstrua...