A role of a hematological profile in assessing the severity of Atopic dermatitis
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2018, Vol 4, Issue 1
Abstract
Background: Atopic dermatitis (AD) is a chronic relapsing eczematous skin disease characterized by pruritus and inflammation. A thorough analysis of relevant object tools like differential leucocyte count can help substantially in assessing AD severity. Objective: This cross-sectionalcase-control study analyzed the correlation between the percentage of eosinophils in differential leucocyte count and severity of AD. Material and Methods: For this study, forty patients with clinical diagnosis of AD based on U.K diagnostic criteria were enrolled. A detailed history and salient presentations were recorded in prestructured proforma. Scoring AD (SCORAD) index was used to evaluate the severity of the disease. Laboratory tests included the differential leucocyte count along with other hematological parameters. All other causes of raised eosinophilia were excluded. Results: In our study, out of 40 patients with atopic dermatitis, 7(17.5%) had elevated eosinophil percentage (>4%) in differential leucocyte count. Out of these 7 patients, 5 were suffering from the severe AD and 2 patients were suffering from themoderate AD. The post-hoc test was conducted for inter-level comparisons where the p-value of comparison between, level 1&3 and level 2&3, was 0.001(highly significant). Conclusion: This study identifies that routine laboratory investigations like differential leucocyte count can serve as an indicator of the severity of atopic dermatitis.
Authors and Affiliations
*Oshin Agrawal, **BB Mahajan, ***Saurabh Sharma, ****Deepak Rana, ***** N. S. Neki
Keywords
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- EP ID EP550420
- DOI 10.22192/ijcrms.2018.04.01.014
- Views 139
- Downloads 0
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