A STATISTICAL ANALYSIS OF LARYNGEAL MALIGNANCIES AT OUR INSTITUTION
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 23
Abstract
BACKGROUND Malignancies of larynx are an increasing global burden with a distribution of approximately 2-5% of all malignancies with an incidence of 3.6/1,00,000 for men and 1.3/1,00,000 for women with a male-to-female ratio of 4:1. Smoking and alcohol are major established risk factors. More than 90-95% of all malignancies are squamous cell type. Three main subsite of laryngeal malignancies are glottis, supraglottis and subglottis. Improved surgical techniques and advanced chemoradiotherapy has increased the overall 5 year survival rate. The above study is statistical analysis of laryngeal malignancies at our institution for a period of one year and analysis of pattern of distribution, aetiology, sites and subsites and causes for recurrence. MATERIALS AND METHODS Based on the statistical data available in the institution for the period of one year from January 2016-December 2016, all laryngeal malignancies were analysed with respect to demographic pattern, age, gender, site, subsite, aetiology, staging, treatment received and probable cause for failure of treatment. Patients were followed up for 12 months period during the study. RESULTS Total number of cases studied are 27 (twenty seven). Male cases are 23 and female cases are 4, male-to-female ratio is 5.7:1, most common age is above 60 years, most common site is supraglottis, most common type is moderately-differentiated squamous cell carcinoma, most common cause for relapse or recurrence is advanced stage of disease and poor differentiation. CONCLUSION The commonest age occurrence at the end of the study is above 60 years and male-to-female ratio is 5.7:1, which is slightly above the international standards. Most common site is supraglottis and not glottis. The relapse and recurrences are higher compared to the international standards.
Authors and Affiliations
Bharathi Mohan Mathan, Elango Kuppuswamy Mohanraj, Kalidass Muthukrishnan, Sumee Venkatesan, Inan Madeswaran
A COMPARATIVE STUDY OF INTRAVENOUS IRON SUCROSE WITH ORAL IRON FERROUS SULPHATE IN TREATMENT OF ANAEMIA IN ANTENATAL MOTHER
BACKGROUND Anaemia is the most common medical disorder in pregnancy. Iron Sucrose is a suitable alternative source of iron which is well tolerated with few mild side effects to combat this massive problem of anaemia. The...
RENAL FUNCTION DERANGEMENT IN HELLP SYNDROME
BACKGROUND HELLP is the acronym for haemolysis, elevated liver enzymes and low platelet count. HELLP syndrome is a form of severe preeclampsia with an incidence of 0.2-0.6% of all pregnancies. The aim of our study is to...
ON THE IMPORTANCE OF PEER INFLUENCE FOR ADOLESCENT NICOTINE USE
BACKGROUND Peers, smoking parents, and media are the sources of social pressure having an overriding influence on adolescents to begin smoking. Drug behaviour of adolescents is highly affected by peer influence. Although...
SINONASAL AND ORBITAL MALIGNANT NEOPLASMS IN PEDIATRIC POPULATION: A STUDY FROM A TERTIARY CARE CENTRE IN INDIA
INTRODUCTION: Paranasal and extra-ocular orbital malignant tumors are comparatively rare in pediatric patients and difficult to diagnose early. Malignant lesions in this region tend to be locally aggressive, often presen...
HEAD-TO-HEAD COMPARISON OF TOLERABILITY AND ACCEPTABILITY OF SINGLE DOSE OF FOUR TOPICAL NSAIDS IN PATIENTS UNDERGOING CATARACT SURGERY: A RANDOMIZED OPEN LABEL PARALLEL GROUP STUDY
Ophthalmic NSAIDs are used to control pain, discomfort and inflammation associated with ocular conditions and also, following ophthalmic cataract surgeries. These drugs can cause ocular discomfort following administratio...