“A STUDY OF ALTERNATE BIOMARKERS IN HIV DISEASE AND EVALUATING THEIR EFFICACY IN PREDICTING T CD4+ CELL COUNTS AND DISEASE PROGRESSION IN RESOURCE POOR SETTINGS IN HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) ERA
Journal Title: INTERNATIONAL JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH - Year 2015, Vol 3, Issue 1
Abstract
Human Immunodeficiency Virus (HIV), the causative agent in AIDS has been a challenge to medical fraternity from the time since it was first discovered in 1983. Traditionally HIV disease and progression, initiation of HAART and response to therapy is monitored by assessing in regular intervals (6 months) the T CD4+ cell counts and plasma HIV/RNA viral load. Resource poor, low and low middle income group countries still have no finances to acquire infrastructure and scientific technology to perform such tests. Very few studies are available that have demonstrated the role of alternate biomarkers that can be used to predict CD4 cell counts and thereby monitor HIV disease progression and HAART.
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