A study of association of serum uric acid and hypertension in the patients at tertiary health care center
Journal Title: Medpulse International Journal of Biochemistry - Year 2017, Vol 4, Issue 1
Abstract
Background: Uric acid (UA), as the final oxidation product of purine catabolism, has been associated with various clinical conditions such as diabetes mellitus (DM) and atherosclerotic disease. Recent studies suggest that UA is a relevant and independent risk factor particularly in patients with hypertension. Aims and Objectives: To study association of Serum Uric acid and Hypertension in the patients at Tertiary health care center. Methodology: This was a cross-sectional study carried out in the Hypertensive patients at the tertiary health care center during the year January 2016 to January 2017, during one year period total 50 hypertensive patients were studied and corresponding 50 normotensive patients were also included randomly into the study. All the patients were investigated for the serum uric acid level. The patients were categorized into Hyperuricemia if (>7.0 mg/dL) Normal Uric acid level (3.4-7.0 mg/dL). The mean uric acid level of hypertensive and normotensive patients also noted. The statistical analysis done by Chi-square test and unpaired t-test calculated by SPSS-19 version software. Result: Majority of the patients were in the age group of >60 were 38%, followed by 50-60 were 24%, 40-50 were 18%, 30-40 were 14%, 20-30 were 6%. The majority of the patients were Male i.e. 64% and females were 36%. The majority of Hypouricemic patients were in the hypertensive patients i.e. 42 % as compared to 22% in normotensive patients where as the Normal Uric acid level was present in the majority of Normotensive patients i.e. 26% as compared to Hypertensive i.e. 10%. This observed difference was statistically significant (X2 = 5.12, df=1, P<0.05). The Mean Uric acid level (Mean±SD) in Normotensive was 3.28 ± 1.76 and in Hypertensive was 6.12 ± 1.93 this observed difference was statistically significant (P<0.001, t = 5.4217 , df = 48). Conclusion: It can be concluded from our study that the majority with hypertensive patients were significantly associated with raised uric acid level.
Authors and Affiliations
Swapna V S, Triveni A Jambale, Mr Anand
Keywords
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- EP ID EP486205
- DOI 10.26611/1002416
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