A STUDY OF CORRELATION OF BODY MASS INDEX AND PEAK EXPIRATORY FLOW RATE WITH FEV1 IN PATIENTS OF COPD
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 20
Abstract
BACKGROUND COPD is an important public health challenge characterized by obstruction to airflow that is not reversible. Low BMI is also considered as an independent negative determinant of survival in patients with COPD. There are few studies comparing association between peak expiratory flow rate (PEFR) and forced expiratory volume in 1st second (FEV1) for severity classification of COPD. The role of PEFR as a substitute of FEV1 in situations and resource limited areas has not been extensively studied. METHODS This was a cross sectional, observational study. The study was conducted in the Respiratory Medicine Department at SRM Medical College Hospital and Research Center, Chennai, Tamilnadu. The study population was selected from among 117 consecutive patients of COPD. BMI was measured in each patient. Both FEV1 and PEFR were obtained at a single visit using spirometer and FEV1, post-bronchodilator FVC, and ratio of FEV1/FVC (FEV1%) were measured and statistically analysed. Data was coded and entered in MS Excel and analysed using the statistical package SPSS version 18. Pearson Correlation test was done for linear relations between quantitative variables. RESULTS Among the 117 study participants, on applying the Pearson correlation test, we found that PEFR (L/min) and post FEV1% predicted were strongly correlated (positive correlation) (r= 0.725, p< 0.001) but same test applied for BMI and post FEV1% predicted were weakly (Positive correlation) correlated ( r= 0.283, p= 0.002). CONCLUSIONS Both BMI and PEFR had positive correlation with post FEV1% predicted. BMI showed weak correlation but PEFR showed strong correlation with FEV1%, hence we can use PEFR as a surrogate marker for daily monitoring in patients with COPD.
Authors and Affiliations
Rabeeh Parambil, Subramanian Suriyan, Nalini Jayanthi Nagesh, Bharath Bharath, Kavitha Devi, Pon Thelac
Keywords
Related Articles
- EP ID EP617792
- DOI 10.14260/jemds/2019/363
- Views 94
- Downloads 0
A STUDY OF BREATHLESSNESS IN PREGNANT FEMALES IN A RURAL SETUP
AIM This cross-sectional study was done to know the number of pregnant females experiencing breathlessness. Breathlessness is a common but a less recognised symptom in pregnancy. This study was done to highlight...
POST CHOLECYSTECTOMY AND THE DYSPEPTIC PATIENT TO IDENTIFYING THE APPROPRIATENESS OF OPERATIVE INTERVENTION IN CHENGALPATTU MEDICAL COLLEGE
BACKGROUND Dyspepsia is defined by the discomfort or pain localised in the upper abdomen. This pain is common with a prevalence of forty to sixty percent in the general population. But often 55% of patients do not have a...
FEASIBILITY AND SAFETY OF FLUOROLESS URETERORENOSCOPY- OUR INSTITUTIONAL EXPERIENCE
BACKGROUND Patients with urolithiasis are exposed to significant amounts of radiation during preoperative workup by means of X-ray, conventional contrast imaging and CECT during surgery and followup. The purpose of this...
AUTOIMMUNE THYROIDITIS IN PREGNANCY- A CROSS SECTIONAL STUDY IN A TERTIARY CARE HOSPITAL OF SOUTHERN ODISHA
BACKGROUND A lot of physiological changes occur during pregnancy due to complex endocrine and immunological alterations. Autoimmune thyroid dysfunction is quite common which is responsible for various fetomaternal compli...
AN UNUSUAL SITE OF EPIDERMOID CYST
Epidermoid cyst is usually due to infection of pilosebaceous gland or due to traumatic migration of epidermis to the deeper structure of skin. They may present in any place of body which is lined by squamous ep...