A STUDY OF CORRELATION OF BODY MASS INDEX AND PEAK EXPIRATORY FLOW RATE WITH FEV1 IN PATIENTS OF COPD

Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 20

Abstract

BACKGROUND COPD is an important public health challenge characterized by obstruction to airflow that is not reversible. Low BMI is also considered as an independent negative determinant of survival in patients with COPD. There are few studies comparing association between peak expiratory flow rate (PEFR) and forced expiratory volume in 1st second (FEV1) for severity classification of COPD. The role of PEFR as a substitute of FEV1 in situations and resource limited areas has not been extensively studied. METHODS This was a cross sectional, observational study. The study was conducted in the Respiratory Medicine Department at SRM Medical College Hospital and Research Center, Chennai, Tamilnadu. The study population was selected from among 117 consecutive patients of COPD. BMI was measured in each patient. Both FEV1 and PEFR were obtained at a single visit using spirometer and FEV1, post-bronchodilator FVC, and ratio of FEV1/FVC (FEV1%) were measured and statistically analysed. Data was coded and entered in MS Excel and analysed using the statistical package SPSS version 18. Pearson Correlation test was done for linear relations between quantitative variables. RESULTS Among the 117 study participants, on applying the Pearson correlation test, we found that PEFR (L/min) and post FEV1% predicted were strongly correlated (positive correlation) (r= 0.725, p< 0.001) but same test applied for BMI and post FEV1% predicted were weakly (Positive correlation) correlated ( r= 0.283, p= 0.002). CONCLUSIONS Both BMI and PEFR had positive correlation with post FEV1% predicted. BMI showed weak correlation but PEFR showed strong correlation with FEV1%, hence we can use PEFR as a surrogate marker for daily monitoring in patients with COPD.

Authors and Affiliations

Rabeeh Parambil, Subramanian Suriyan, Nalini Jayanthi Nagesh, Bharath Bharath, Kavitha Devi, Pon Thelac

Keywords

Related Articles

&nbsp;INFLAMMATORY PSEUDOTUMOUR OF THE LARYNX: A CASE REPORT

&nbsp; [b]INTRODUCTION[/b]: Inflammatory Pseudotumour (IPT) is a benign proliferation of tissue but has a destructive potential of the affected area. It is also called Inflammatory Myofibroblastic tumour (IMT). Ini...

IMPORTANCE OF ECHOCARDIOGRAPHIC STRAIN IMAGING TEST FOR ASSESSMENT OF VIABILITY IN PATIENTS OF POST MYOCARDIAL INFARCTION WITH LEFT VENTRICULAR SYSTOLIC DYSFUNCTION AND ITS COMPARISON WITH SPECT

BACKGROUND Left ventricular systolic dysfunction following myocardial infarction increases risks of heart failure and sudden death. Identification of viable myocardium is important before revascularisation techniques. Th...

&nbsp;THE EFFICACY OF FIBRIN GLUE Vs SUTURES FOR ATTACHING CONJUNCTIVAL AUTOGRAFTS AFTER PTERYGIUM EXCISION: A RANDOMIZED CLINICAL TRIAL

&nbsp;BACKGROUND AND OBJECTIVE Fibrin glues have been used in an array of ophthalmic procedures such as conjunctival closure in strabismus, vitreoretinal and glaucoma surgery. The present study was undertaken to asses...

&nbsp;TO DETERMINE THE USE OF AN LNG-IUS FOR CONSERVATIVE MANAGEMENT IN WOMEN WITH SYMPTOMATIC MILD TO MODERATE ENDOMETRIOSIS

&nbsp;Medical treatment of endometriosis, a condition which significantly affects the quality of life in only 10–15% of women in the reproductive years, rest have no improvement. Although oral progestogens are effect...

SPECTRUM OF ADVERSE EFFECTS OF HAART THERAPY AMONG HIV INFECTED INDIVIDUALS- A PROSPECTIVE STUDY

BACKGROUND India is the world’s second largest country with HIV. The prevalence of HIV among Indian adults is 0.26%. In 2015, India had 2.1 million people living with HIV. HAART has reduced HIV mortality significantly. I...

Download PDF file
  • EP ID EP617792
  • DOI 10.14260/jemds/2019/363
  • Views 56
  • Downloads 0

How To Cite

Rabeeh Parambil, Subramanian Suriyan, Nalini Jayanthi Nagesh, Bharath Bharath, Kavitha Devi, Pon Thelac (2019). A STUDY OF CORRELATION OF BODY MASS INDEX AND PEAK EXPIRATORY FLOW RATE WITH FEV1 IN PATIENTS OF COPD. Journal of Evolution of Medical and Dental Sciences, 8(20), 1643-1646. https://europub.co.uk/articles/-A-617792